ADPGK and TCAP

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		ADPGK	TCAP
Description		ADP dependent glucokinase	titin-cap
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Cytosol Z Disc I Band
	Molecular Function	ADP-specific Glucokinase Activity Metal Ion Binding	Protein Binding Structural Constituent Of Muscle Protein-macromolecule Adaptor Activity Titin Binding BMP Binding Transmembrane Transporter Binding FATZ Binding Titin Z Domain Binding
	Biological Process	Carbohydrate Metabolic Process Glucose Metabolic Process Glycolytic Process Through Glucose-6-phosphate	Somitogenesis Skeletal Muscle Contraction Cardiac Muscle Hypertrophy Adult Heart Development Cardiac Muscle Hypertrophy In Response To Stress Skeletal Muscle Thin Filament Assembly Skeletal Muscle Myosin Thick Filament Assembly Otic Vesicle Formation Response To Muscle Stretch Detection Of Muscle Stretch Sarcomere Organization Sarcomerogenesis Detection Of Mechanical Stimulus Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Cell Development Cardiac Muscle Contraction Protein-containing Complex Assembly
Pathways		Glycolysis	Striated Muscle Contraction
Drugs
Diseases
GWAS		Adult body size ( 32376654) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Hand grip strength ( 29691431) Triglyceride levels ( 28334899) Urate levels ( 23263486) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Alcohol consumption ( 31358974) Asthma ( 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Pancreatic ductal adenocarcinoma ( 30541042) Refractive error ( 32231278) Ulcerative colitis ( 20228799)
Interacting Genes		5 interacting genes: GDF9 OGT TADA3 TCAP UBQLN4	39 interacting genes: ADPGK ANKRD2 ASB6 ATXN1 BLZF1 C19orf54 CDCA4 CHORDC1 CRK ENO1 ENO3 FAM153B FAS FYN GSK3B HSPA8 HSPB2 HSPB3 HSPG2 IKZF3 KLHL41 KRTAP19-7 LAMTOR5 LHX4 MDM2 MSTN MYOZ1 MYOZ3 NUP133 PAX7 PDPK1 RELA SAPCD1 SIVA1 TRIM54 TRIM55 TRIM63 TTC19 TTN
Entrez ID		83440	8557
HPRD ID		12429	05133
Ensembl ID		ENSG00000159322	ENSG00000173991
Uniprot IDs		Q9BRR6	A2TDC0 O15273
PDB IDs			1YA5 2F8V
Enriched GO Terms of Interacting Partners?
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