GDF9 and PCDHA4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GDF9	PCDHA4
Description		growth differentiation factor 9	protocadherin alpha 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Integral Component Of Plasma Membrane
	Molecular Function	Cytokine Activity Growth Factor Activity Type I Activin Receptor Binding	Calcium Ion Binding Protein Binding Identical Protein Binding
	Biological Process	Oocyte Growth Transforming Growth Factor Beta Receptor Signaling Pathway Female Gamete Generation Positive Regulation Of Cell Population Proliferation Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Cell Growth BMP Signaling Pathway SMAD Protein Signal Transduction Regulation Of Progesterone Secretion	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Nervous System Development
Pathways
Drugs
Diseases
GWAS		Asthma ( 31619474)	Neutrophil count ( 27863252) Schizophrenia ( 28991256 29483656) Sum basophil neutrophil counts ( 27863252)
Interacting Genes		46 interacting genes: ACVR2A ADPGK ANXA7 APLP1 BMP15 BMPR1A BMPR1B BMPR2 BTBD2 CDKN1A CDKN2C CRELD1 DLEU1 DNM2 FOXG1 FXYD6 GADD45G HSPA9 ILF3 KDM1A KIF22 LSM3 MOB4 MPHOSPH6 MYCBP NDUFB9 ORAI2 PABPC4 PAFAH1B3 PCDHA4 PCYT2 PMF1 PRKRA PSMD11 RAB27A RSRC1 S100A8 SAT1 SERPINB9 SMN1 SNRPG STRN4 TDGF1 TK1 TRIB3 WASHC3	16 interacting genes: APLP1 CCDC90B EEF1A1 ERG28 GAPDH GDF9 IGSF21 LRIF1 RBM48 RELN SETDB1 SGTA TLE1 TP53 UBQLN1 UNC119
Entrez ID		2661	56144
HPRD ID		03560	07322
Ensembl ID		ENSG00000164404	ENSG00000204967
Uniprot IDs		B4DXG3 O60383	Q59H34 Q9UN74
PDB IDs
Enriched GO Terms of Interacting Partners?
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