SNX27 and HLCS

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		SNX27	HLCS
Description		sorting nexin 27	holocarboxylase synthetase
Image			No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Nucleoplasm Endosome Early Endosome Cytosol Early Endosome Membrane	Chromatin Nuclear Lamina Cytoplasm Mitochondrion Cytosol Nuclear Matrix
	Molecular Function	Protein Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol Binding	Biotin-[acetyl-CoA-carboxylase] Ligase Activity Biotin-[methylcrotonoyl-CoA-carboxylase] Ligase Activity Biotin-[methylmalonyl-CoA-carboxytransferase] Ligase Activity Biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] Ligase Activity Protein Binding ATP Binding Biotin Binding Biotin-protein Ligase Activity Enzyme Binding
	Biological Process	Establishment Of Natural Killer Cell Polarity Intracellular Protein Transport Signal Transduction Endosome To Lysosome Transport Endosomal Transport Endocytic Recycling	Biotin Metabolic Process Protein Biotinylation Histone Modification Response To Biotin Histone Biotinylation
Pathways			Biotin transport and metabolism Defective HLCS causes multiple carboxylase deficiency
Drugs			Biotin
Diseases
GWAS		Body mass index ( 26426971)	Developmental language disorder ( 27016271) Developmental language disorder (linguistic errors) ( 27016271) Hematocrit ( 32888494) Hemoglobin ( 32888494) Intracranial aneurysm ( 29531279) Night sleep phenotypes ( 27126917) Red blood cell count ( 32888494) Seasonality and depression ( 30217971)
Interacting Genes		10 interacting genes: ACE2 AKT2 APP DGKZ HLCS PNPLA3 PTEN RPS6KA1 SELP SUMO2	17 interacting genes: ACACB ANKRD29 BACH1 DDX52 IFNAR2 IFNGR2 IFT20 KRTAP5-9 LANCL2 MED19 NGB POT1 SNX27 SOD1 SPATA46 TGM3 WIPF1
Entrez ID		81609	3141
HPRD ID		11591	08360
Ensembl ID		ENSG00000143376	ENSG00000159267
Uniprot IDs		A0A2R8Y8A7 Q96L92	P50747
PDB IDs		4HAS 5ZN9 6SAK
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?