TARS2 and SYPL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TARS2	SYPL1
Description		threonyl-tRNA synthetase 2, mitochondrial	synaptophysin like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Mitochondrial Matrix	Integral Component Of Plasma Membrane Integral Component Of Membrane Secretory Granule Integral Component Of Synaptic Vesicle Membrane Synaptic Vesicle Membrane Melanosome Extracellular Exosome
	Molecular Function	Aminoacyl-tRNA Editing Activity Threonine-tRNA Ligase Activity Protein Binding ATP Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Threonyl-tRNA Aminoacylation Mitochondrial Threonyl-tRNA Aminoacylation Aminoacyl-tRNA Metabolism Involved In Translational Fidelity	Chemical Synaptic Transmission
Pathways		Mitochondrial tRNA aminoacylation
Drugs		Threonine
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823 27494321) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) LDL cholesterol levels ( 32203549) Liver enzyme levels (alanine transaminase) ( 33972514) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Plateletcrit ( 32888494) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		15 interacting genes: ANP32E ARL6IP1 ASB6 CIART FKBP7 GABPB2 H3C14 HOMEZ PLIN3 SLC17A9 SYPL1 TARS3 TNFAIP8L2 TNFRSF10D ZNF687	10 interacting genes: ARFGAP3 CIB3 LMNA PBX3 PPIF RBFA SDCBP TARS2 TEX44 VAMP2
Entrez ID		80222	6856
HPRD ID		18148	15459
Ensembl ID		ENSG00000143374	ENSG00000008282
Uniprot IDs		Q9BW92 U3KQG0	A4D0R1 Q16563
PDB IDs
Enriched GO Terms of Interacting Partners?
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