TARS2 and CIART

		TARS2	CIART
Description		threonyl-tRNA synthetase 2, mitochondrial	circadian associated repressor of transcription
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Mitochondrial Matrix	Nucleus PML Body
	Molecular Function	Aminoacyl-tRNA Editing Activity Threonine-tRNA Ligase Activity Protein Binding ATP Binding Protein Homodimerization Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Protein Binding E-box Binding
	Biological Process	Threonyl-tRNA Aminoacylation Mitochondrial Threonyl-tRNA Aminoacylation Aminoacyl-tRNA Metabolism Involved In Translational Fidelity	Circadian Regulation Of Gene Expression Locomotor Rhythm Negative Regulation Of Transcription, DNA-templated
Pathways		Mitochondrial tRNA aminoacylation
Drugs		Threonine
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823 27494321) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) LDL cholesterol levels ( 32203549) Liver enzyme levels (alanine transaminase) ( 33972514) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Plateletcrit ( 32888494) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		15 interacting genes: ANP32E ARL6IP1 ASB6 CIART FKBP7 GABPB2 H3C14 HOMEZ PLIN3 SLC17A9 SYPL1 TARS3 TNFAIP8L2 TNFRSF10D ZNF687	4 interacting genes: APP DAB1 NFYC TARS2
Entrez ID		80222	148523
HPRD ID		18148	14081
Ensembl ID		ENSG00000143374	ENSG00000159208
Uniprot IDs		Q9BW92 U3KQG0	Q5TB12 Q8N365 Q8WVX4
PDB IDs
Enriched GO Terms of Interacting Partners?
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