SYPL1 and TARS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SYPL1	TARS2
Description		synaptophysin like 1	threonyl-tRNA synthetase 2, mitochondrial
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Integral Component Of Membrane Secretory Granule Integral Component Of Synaptic Vesicle Membrane Synaptic Vesicle Membrane Melanosome Extracellular Exosome	Cellular_component Mitochondrial Matrix
	Molecular Function	Protein Binding	Aminoacyl-tRNA Editing Activity Threonine-tRNA Ligase Activity Protein Binding ATP Binding Protein Homodimerization Activity
	Biological Process	Chemical Synaptic Transmission	Threonyl-tRNA Aminoacylation Mitochondrial Threonyl-tRNA Aminoacylation Aminoacyl-tRNA Metabolism Involved In Translational Fidelity
Pathways			Mitochondrial tRNA aminoacylation
Drugs			Threonine
Diseases
GWAS			Alanine aminotransferase levels ( 33547301) Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823 27494321) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) LDL cholesterol levels ( 32203549) Liver enzyme levels (alanine transaminase) ( 33972514) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Plateletcrit ( 32888494) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		10 interacting genes: ARFGAP3 CIB3 LMNA PBX3 PPIF RBFA SDCBP TARS2 TEX44 VAMP2	15 interacting genes: ANP32E ARL6IP1 ASB6 CIART FKBP7 GABPB2 H3C14 HOMEZ PLIN3 SLC17A9 SYPL1 TARS3 TNFAIP8L2 TNFRSF10D ZNF687
Entrez ID		6856	80222
HPRD ID		15459	18148
Ensembl ID		ENSG00000008282	ENSG00000143374
Uniprot IDs		A4D0R1 Q16563	Q9BW92 U3KQG0
PDB IDs
Enriched GO Terms of Interacting Partners?
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