TARS2 and TARS3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TARS2	TARS3
Description		threonyl-tRNA synthetase 2, mitochondrial	threonyl-tRNA synthetase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Mitochondrial Matrix	Cellular_component Nucleus Cytoplasm
	Molecular Function	Aminoacyl-tRNA Editing Activity Threonine-tRNA Ligase Activity Protein Binding ATP Binding Protein Homodimerization Activity	Molecular_function Threonine-tRNA Ligase Activity Protein Binding ATP Binding
	Biological Process	Threonyl-tRNA Aminoacylation Mitochondrial Threonyl-tRNA Aminoacylation Aminoacyl-tRNA Metabolism Involved In Translational Fidelity	Threonyl-tRNA Aminoacylation Biological_process
Pathways		Mitochondrial tRNA aminoacylation
Drugs		Threonine
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823 27494321) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) LDL cholesterol levels ( 32203549) Liver enzyme levels (alanine transaminase) ( 33972514) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Plateletcrit ( 32888494) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		15 interacting genes: ANP32E ARL6IP1 ASB6 CIART FKBP7 GABPB2 H3C14 HOMEZ PLIN3 SLC17A9 SYPL1 TARS3 TNFAIP8L2 TNFRSF10D ZNF687	11 interacting genes: ARPC3 ARRDC4 ATF4 DNM1P46 ECSIT LGALS14 LRRC28 SELENOS TARS1 TARS2 TM2D3
Entrez ID		80222	123283
HPRD ID		18148	15469
Ensembl ID		ENSG00000143374	ENSG00000185418
Uniprot IDs		Q9BW92 U3KQG0	A2RTX5
PDB IDs
Enriched GO Terms of Interacting Partners?
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