TARS2 and ARL6IP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TARS2	ARL6IP1
Description		threonyl-tRNA synthetase 2, mitochondrial	ADP ribosylation factor like GTPase 6 interacting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Mitochondrial Matrix	Sec61 Translocon Complex Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Aminoacyl-tRNA Editing Activity Threonine-tRNA Ligase Activity Protein Binding ATP Binding Protein Homodimerization Activity	Protein Binding Identical Protein Binding
	Biological Process	Threonyl-tRNA Aminoacylation Mitochondrial Threonyl-tRNA Aminoacylation Aminoacyl-tRNA Metabolism Involved In Translational Fidelity	Positive Regulation Of L-glutamate Import Across Plasma Membrane Cotranslational Protein Targeting To Membrane Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Endoplasmic Reticulum Tubular Network Formation Regulation Of Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Membrane Organization
Pathways		Mitochondrial tRNA aminoacylation
Drugs		Threonine
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823 27494321) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) LDL cholesterol levels ( 32203549) Liver enzyme levels (alanine transaminase) ( 33972514) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Plateletcrit ( 32888494) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Caffeine consumption from coffee or tea ( 33287642) Refractive error ( 32231278)
Interacting Genes		15 interacting genes: ANP32E ARL6IP1 ASB6 CIART FKBP7 GABPB2 H3C14 HOMEZ PLIN3 SLC17A9 SYPL1 TARS3 TNFAIP8L2 TNFRSF10D ZNF687	77 interacting genes: ACSF2 AQP6 ARL4D ARL6 C19orf18 CERT1 DIABLO EHD3 EMP1 F2RL1 FBXW7 FDFT1 FXR2 GAD2 GAS8 GOLPH3 GOLPH3L GORASP2 GPR151 GPR152 HGS HMGCL HSD17B13 INPP5K LMNA MCEMP1 MFSD14B MFSD5 MGST3 MIEF2 MTERF3 MYG1 NAPB NDRG4 NTAQ1 NUDT3 PAM16 PBX3 PICK1 PTPN9 RAB33A REEP6 RETREG3 RNF5 SDCBP SENP2 SHISA5 SHMT2 SLC10A6 SLC13A1 SLC35C2 SNX1 SNX10 SNX11 SNX12 SNX15 SNX2 SNX3 SNX4 SNX8 SPG21 STARD4 SUCLA2 TARS2 TFAM TMED8 TMEM14B TMEM248 TMEM258 TUFM UBE2I VMA21 WDFY2 WIPI2 YIPF4 ZFYVE21 ZNF391
Entrez ID		80222	23204
HPRD ID		18148	09641
Ensembl ID		ENSG00000143374	ENSG00000170540
Uniprot IDs		Q9BW92 U3KQG0	A0A024QYV7 Q15041
PDB IDs
Enriched GO Terms of Interacting Partners?
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