ARL6IP1 and WIPI2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		ARL6IP1	WIPI2
Description		ADP ribosylation factor like GTPase 6 interacting protein 1	WD repeat domain, phosphoinositide interacting 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Sec61 Translocon Complex Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane	Phagophore Assembly Site Nucleoplasm Autophagosome Cytosol Membrane Extrinsic Component Of Membrane Protein-containing Complex Phagophore Assembly Site Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Positive Regulation Of L-glutamate Import Across Plasma Membrane Cotranslational Protein Targeting To Membrane Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Endoplasmic Reticulum Tubular Network Formation Regulation Of Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Membrane Organization	Autophagosome Assembly Autophagy Of Mitochondrion Protein Lipidation Cellular Response To Starvation Protein Localization To Phagophore Assembly Site Autophagy Of Nucleus Protein Lipidation Involved In Autophagosome Assembly Autophagosome Maturation Xenophagy
Pathways			Macroautophagy
Drugs
Diseases
GWAS		Caffeine consumption from coffee or tea ( 33287642) Refractive error ( 32231278)	Bone mineral density x blood lead interaction in current smokers (1df test) ( 29518117) Bone mineral density x blood lead interaction in current smokers (2df test) ( 29518117) High light scatter reticulocyte count ( 32888494) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494 27863252) Red blood cell count ( 32888494)
Interacting Genes		77 interacting genes: ACSF2 AQP6 ARL4D ARL6 C19orf18 CERT1 DIABLO EHD3 EMP1 F2RL1 FBXW7 FDFT1 FXR2 GAD2 GAS8 GOLPH3 GOLPH3L GORASP2 GPR151 GPR152 HGS HMGCL HSD17B13 INPP5K LMNA MCEMP1 MFSD14B MFSD5 MGST3 MIEF2 MTERF3 MYG1 NAPB NDRG4 NTAQ1 NUDT3 PAM16 PBX3 PICK1 PTPN9 RAB33A REEP6 RETREG3 RNF5 SDCBP SENP2 SHISA5 SHMT2 SLC10A6 SLC13A1 SLC35C2 SNX1 SNX10 SNX11 SNX12 SNX15 SNX2 SNX3 SNX4 SNX8 SPG21 STARD4 SUCLA2 TARS2 TFAM TMED8 TMEM14B TMEM248 TMEM258 TUFM UBE2I VMA21 WDFY2 WIPI2 YIPF4 ZFYVE21 ZNF391	16 interacting genes: ARL6IP1 COPS6 DDB1 DGAT2L6 FKBP7 HUWE1 MRRF MTOR OPTN POT1 RABAC1 REEP6 RPTOR STRN4 SYP TERF2IP
Entrez ID		23204	26100
HPRD ID		09641	15679
Ensembl ID		ENSG00000170540	ENSG00000157954
Uniprot IDs		A0A024QYV7 Q15041	A0A024R823 Q9Y4P8
PDB IDs
Enriched GO Terms of Interacting Partners?
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