MCMBP and MCM6

Number of citations of the paper that reports this interaction (PubMedID 17296731)
26

Data Source:
BioGRID (affinity chromatography technology, pull down)

		MCMBP	MCM6
Description		minichromosome maintenance complex binding protein	minichromosome maintenance complex component 6
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Cell Junction	Chromosome, Telomeric Region Nucleus Nucleoplasm MCM Complex CMG Complex
	Molecular Function	Chromatin Binding Protein Binding	DNA Helicase Activity Single-stranded DNA Binding Protein Binding ATP Binding ATP Hydrolysis Activity Single-stranded DNA Helicase Activity Identical Protein Binding Single-stranded 3'-5' DNA Helicase Activity
	Biological Process	DNA-dependent DNA Replication Sister Chromatid Cohesion Cell Division	Double-strand Break Repair Via Break-induced Replication DNA Replication DNA Unwinding Involved In DNA Replication DNA Replication Initiation Mitotic DNA Replication
Pathways			Activation of ATR in response to replication stress Unwinding of DNA Assembly of the pre-replicative complex Orc1 removal from chromatin Activation of the pre-replicative complex Switching of origins to a post-replicative state
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Height ( 28552196)	Aspartate aminotransferase levels ( 33547301) Body fat percentage and LDL-C (pairwise) ( 33619380) Body mass index ( 25673413) Body mass index and LDL-C (pairwise) ( 33619380) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Hip circumference ( 25673412) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)
Interacting Genes		15 interacting genes: ASL DBF4 DDIT3 FKBP5 KEAP1 MCM3 MCM4 MCM5 MCM6 MCM7 PRTFDC1 RWDD2A SNW1 USP7 ZNF474	37 interacting genes: C2CD6 CCNA1 CDC42 CDC45 CDC7 CDKN2A CDT1 CHEK1 CRLS1 DBF4 ESCO2 FAM161A GMNN HSPB1 IL36RN ING5 MCM10 MCM2 MCM3 MCM4 MCM7 MCM8 MCMBP MLLT3 MTDH NUDT2 ORC1 ORC2 ORC4 ORC6 PSMA1 RPA1 SCNM1 SMC1A SNRPB2 TRIM28 ZBTB9
Entrez ID		79892	4175
HPRD ID		07624	03485
Ensembl ID		ENSG00000197771	ENSG00000076003
Uniprot IDs		A0A0S2Z5P5 Q9BTE3	Q14566
PDB IDs		4KG9	2KLQ 2LE8 6XTX 6XTY
Enriched GO Terms of Interacting Partners?
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