MCMBP and FKBP5

Number of citations of the paper that reports this interaction (PubMedID 25036637)
154

Data Source:
BioGRID (two hybrid, affinity chromatography technology, affinity chromatography technology)

		MCMBP	FKBP5
Description		minichromosome maintenance complex binding protein	FKBP prolyl isomerase 5
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Cell Junction	Nucleoplasm Cytoplasm Cytosol Membrane Extracellular Exosome
	Molecular Function	Chromatin Binding Protein Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding Heat Shock Protein Binding
	Biological Process	DNA-dependent DNA Replication Sister Chromatid Cohesion Cell Division	Protein Peptidyl-prolyl Isomerization Protein Folding Response To Bacterium Chaperone-mediated Protein Folding
Pathways			HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand ESR-mediated signaling MECP2 regulates neuronal receptors and channels
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Height ( 28552196)	Autoimmune thyroid disease ( 32581359) Birth weight ( 31043758) Body shape index ( 34021172) Colorectal cancer or advanced adenoma ( 30510241) Coronary artery disease ( 29212778) Eosinophil counts ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Hip circumference adjusted for BMI ( 34021172) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) Offspring birth weight ( 31043758) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White blood cell count ( 27863252)
Interacting Genes		15 interacting genes: ASL DBF4 DDIT3 FKBP5 KEAP1 MCM3 MCM4 MCM5 MCM6 MCM7 PRTFDC1 RWDD2A SNW1 USP7 ZNF474	15 interacting genes: APP CHUK ESR1 FES GLMN HSF1 HSP90AA1 IKBKE MAPT MCMBP NR2C2 OGT PGR STIP1 USP49
Entrez ID		79892	2289
HPRD ID		07624	04019
Ensembl ID		ENSG00000197771	ENSG00000096060
Uniprot IDs		A0A0S2Z5P5 Q9BTE3	Q13451 Q2TA84
PDB IDs		4KG9	1KT0 3O5D 3O5E 3O5F 3O5G 3O5I 3O5J 3O5K 3O5L 3O5M 3O5O 3O5P 3O5Q 3O5R 4DRH 4DRI 4DRK 4DRM 4DRN 4DRO 4DRP 4DRQ 4JFI 4JFJ 4JFK 4JFL 4JFM 4R0X 4TW6 4TW7 4TX0 4W9O 4W9P 4W9Q 5BXJ 5DIT 5DIU 5DIV 5NJX 5OBK 5OMP 6SAF 6TX4 6TX5 6TX6 6TX7 6TX8 6TX9 6TXX
Enriched GO Terms of Interacting Partners?
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