MCMBP and MCM4

Number of citations of the paper that reports this interaction (PubMedID 17296731)
26

Data Source:
BioGRID (affinity chromatography technology, pull down)

		MCMBP	MCM4
Description		minichromosome maintenance complex binding protein	minichromosome maintenance complex component 4
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Cell Junction	Chromosome, Telomeric Region Nucleus Nucleoplasm Membrane MCM Complex CMG Complex
	Molecular Function	Chromatin Binding Protein Binding	DNA Helicase Activity Single-stranded DNA Binding Protein Binding ATP Binding ATP Hydrolysis Activity Single-stranded DNA Helicase Activity
	Biological Process	DNA-dependent DNA Replication Sister Chromatid Cohesion Cell Division	Double-strand Break Repair Via Break-induced Replication DNA Replication DNA Unwinding Involved In DNA Replication DNA Strand Elongation Involved In DNA Replication Mitotic DNA Replication Initiation
Pathways			Activation of ATR in response to replication stress Unwinding of DNA Assembly of the pre-replicative complex Orc1 removal from chromatin Activation of the pre-replicative complex Switching of origins to a post-replicative state
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Height ( 28552196)	Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Eosinophil percentage of white cells ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 27863252) Reticulocyte count ( 32888494)
Interacting Genes		15 interacting genes: ASL DBF4 DDIT3 FKBP5 KEAP1 MCM3 MCM4 MCM5 MCM6 MCM7 PRTFDC1 RWDD2A SNW1 USP7 ZNF474	27 interacting genes: CCNA1 CDC5L CDC7 CDK1 CDK2 CDT1 DBF4 EP300 ESCO2 LIG4 MCM2 MCM3 MCM6 MCM7 MCM8 MCMBP ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 RPA1 SSRP1 SUMO2 SUPT16H TLX2
Entrez ID		79892	4173
HPRD ID		07624	09094
Ensembl ID		ENSG00000197771	ENSG00000104738
Uniprot IDs		A0A0S2Z5P5 Q9BTE3	B3KMX0 B4DLA6 P33991
PDB IDs		4KG9	6XTX 6XTY
Enriched GO Terms of Interacting Partners?
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