RAP1GDS1 and ABCB7

		RAP1GDS1	ABCB7
Description		Rap1 GTPase-GDP dissociation stimulator 1	ATP binding cassette subfamily B member 7
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Cytosol Extracellular Exosome	Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane
	Molecular Function	GTPase Activator Activity Protein Binding	Protein Binding ATP Binding Heme Transmembrane Transporter Activity ATPase-coupled Transmembrane Transporter Activity Protein Homodimerization Activity ABC-type Iron-sulfur Cluster Transporter Activity
	Biological Process	Vascular Associated Smooth Muscle Contraction Myosin Filament Assembly Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Positive Regulation Of GTPase Activity Positive Regulation Of Mitochondrial Calcium Ion Concentration	Cellular Iron Ion Homeostasis Heme Transport Iron-sulfur Cluster Assembly Iron Ion Transmembrane Transport Iron Ion Homeostasis Transmembrane Transport Positive Regulation Of Heme Biosynthetic Process Iron-sulfur Cluster Export From The Mitochondrion Positive Regulation Of Iron-sulfur Cluster Assembly Negative Regulation Of Reactive Oxygen Species Biosynthetic Process
Pathways		RHOT2 GTPase cycle RHOT1 GTPase cycle	Mitochondrial ABC transporters Cytosolic iron-sulfur cluster assembly
Drugs
Diseases
GWAS		Biochemical measures ( 19260141) Response to fenofibrate (total cholesterol levels) ( 27002377) Suicidality in mood disorders ( 33783297) Suicide attempt severity in mood disorders ( 33783297)	Metabolite levels ( 23823483)
Interacting Genes		28 interacting genes: ABCB7 ANTXR2 CDC42 DIRAS1 DIRAS2 DOC2A EGFR HRAS KIFAP3 KRAS LEF1 MBIP MED28 NRAS OGT PLEKHB1 PTPRF PUF60 RAB6B RAC1 RAP1A RAP2B RAP2C RHOA RNF19B RRAS RRAS2 ZNF451	4 interacting genes: APP FECH RAP1GDS1 UBC
Entrez ID		5910	22
HPRD ID		11763	02137
Ensembl ID		ENSG00000138698	ENSG00000131269
Uniprot IDs		B3KNU0 P52306 Q6U7G8	A0A087WW65 A0A0S2Z2Z3 O75027
PDB IDs		5XGC 5ZHX
Enriched GO Terms of Interacting Partners?
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