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ZRANB1 and CARD9
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
86
Data Source:
BioGRID
(two hybrid)
ZRANB1
CARD9
Description
zinc finger RANBP2-type containing 1
caspase recruitment domain family member 9
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Intracellular Membrane-bounded Organelle
Cytoplasm
Cytosol
Plasma Membrane
CBM Complex
Protein-containing Complex
Molecular Function
Thiol-dependent Deubiquitinase
Protein Binding
Metal Ion Binding
K63-linked Polyubiquitin Modification-dependent Protein Binding
Protein Binding
Protein Homodimerization Activity
Protein Self-association
Metal Ion Binding
CARD Domain Binding
Biological Process
Cytoskeleton Organization
Wnt Signaling Pathway
Cell Migration
Regulation Of Cell Morphogenesis
Positive Regulation Of Wnt Signaling Pathway
Protein K29-linked Deubiquitination
Protein K63-linked Deubiquitination
Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Protein K33-linked Deubiquitination
Positive Regulation Of Cytokine Production
Neutrophil Mediated Immunity
I-kappaB Kinase/NF-kappaB Signaling
Response To Xenobiotic Stimulus
Immunoglobulin Mediated Immune Response
Response To Peptidoglycan
Response To Muramyl Dipeptide
Regulation Of Interleukin-2 Production
Positive Regulation Of Chemokine Production
Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Production
Positive Regulation Of Interleukin-17 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Stress-activated MAPK Cascade
Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Exogenous DsRNA
Positive Regulation Of Innate Immune Response
Positive Regulation Of JNK Cascade
Host-mediated Regulation Of Intestinal Microbiota Composition
Defense Response To Gram-positive Bacterium
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Homooligomerization
Defense Response To Virus
Antifungal Innate Immune Response
Positive Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of T-helper 17 Type Immune Response
Pathways
Degradation of beta-catenin by the destruction complex
Ovarian tumor domain proteases
NOD1/2 Signaling Pathway
CLEC7A (Dectin-1) signaling
Drugs
Diseases
GWAS
Blood urea nitrogen levels (
31152163
)
Creatine kinase levels (
29403010
)
Height (
25429064
31562340
)
Lung cancer (
34062886
)
Acute insulin response (insulin secretion adjusted) (
28490609
)
Ankylosing spondylitis (
23749187
21743469
)
Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) (
26974007
)
Crohn's disease (
28067908
22936669
21102463
)
Hip circumference adjusted for BMI (
34021172
)
IgA nephropathy (
25305756
)
Inflammatory bowel disease (
28067908
23128233
)
Joint damage in rheumatoid arthritis (
26498133
)
Large artery stroke (
28265093
)
Monocyte chemoattractant protein-1 levels (
23017229
)
Obesity-related traits (
23251661
)
Pediatric autoimmune diseases (
26301688
)
Takayasu arteritis (
33308445
)
Ulcerative colitis (
19915572
28067908
20228799
21297633
)
Interacting Genes
153 interacting genes:
AKT1
ANKRD11
AP1M1
ARHGEF5
ARRDC2
ARRDC3
BAHD1
BRD1
BYSL
C1orf35
CARD9
CBX7
CBX8
CCDC120
CCDC13
CCDC185
CCDC187
CCNL1
CDC45
CDC5L
CDK18
CDKL3
CNNM3
CORO7
CPNE7
CSNK1A1
CWF19L2
DCX
DDX6
DNAJB13
DTNB
DUSP13
EHHADH
EIF3D
ENKD1
ERF
FAIM
FAM124B
FAM161A
FAM161B
FAM214B
FAM50B
FARS2
FNDC11
GADD45GIP1
GAS2L2
GEM
GLIS2
GPANK1
GPKOW
HOXB5
HOXC8
IL16
INO80B
IP6K3
IQUB
JRK
KANK2
KIF9
KIFC3
LENG1
LMO3
LNX1
MAGEB4
MAGOH
MCRS1
METAP1
METTL21A
MFAP1
MID2
MPPED1
MYEF2
NEK6
NUDT16L1
NUDT21
PBLD
PHF1
PHF19
PKN1
PLEKHN1
PNMA5
POLDIP3
POLL
POLR1C
PPP1R18
PRPF18
PRPF3
PRPF31
PSPC1
QARS1
RAPGEF3
RASAL3
RHOBTB3
RNPS1
SDCBP
SNCA
STAMBPL1
STK19
SUV39H1
SYT17
SYTL4
TBC1D3
TBC1D30
TBC1D3B
TBC1D3C
TBC1D3G
TBC1D3K
TCEA2
TCEANC
THAP7
TIE1
TLE5
TNS4
TOLLIP
TRAF3IP3
TRAF4
TRAF6
TRAPPC2
TRAPPC2B
TSGA10IP
TSPYL4
TSTD2
TWIST1
UBASH3A
UBC
UBE2S
USP2
UVRAG
VAV3
VEZF1
WT1
XRCC5
ZBTB24
ZBTB47
ZNF124
ZNF17
ZNF250
ZNF408
ZNF417
ZNF438
ZNF490
ZNF497
ZNF552
ZNF575
ZNF581
ZNF587
ZNF599
ZNF629
ZNF648
ZNF764
ZNF775
ZNF792
ZNF837
138 interacting genes:
ABLIM1
AMOTL2
AXIN1
BCL10
BLZF1
C1orf94
C2CD6
CABP2
CARD10
CBX8
CCDC13
CCDC136
CCDC85B
CCDC88B
CCHCR1
CDC37
CDCA7L
CDK2AP1
CEP57L1
CEP70
CSNK2A1
CWF19L2
DAXX
DISC1
DUSP13
DVL2
EFHC2
EIF4A3
EIF4E2
FAM124B
FAM161A
FAM161B
FAM50B
FAM90A1
FOXD4L1
GAS8
GEM
HMBOX1
HOXB5
HSF2BP
IHO1
IKZF3
INO80B
IQCE
KANK2
KCTD9
KIAA0408
KIAA1328
KIF9
KIFC3
KRT15
KRT16
KRT19
KRT31
KRT40
KRT75
KRTAP10-1
KRTAP10-3
KRTAP10-5
KRTAP5-7
L3MBTL2
LENG1
LMO1
LMO3
LNX1
LZTS1
LZTS2
MCRS1
MEOX2
MFAP1
MID2
MYO15B
NECAB2
NTAQ1
PAK5
PBX2
PHC2
PIBF1
PICK1
PKP2
PNMA5
PPP1R18
PRPF18
PSMA4
RBAK
RTP5
SAXO1
SCNM1
SHISA6
SLAIN1
SSX2IP
STMN3
STX11
SUMO1
TASOR2
TCEANC
TCL1A
TEX33
TFIP11
TLE5
TNFAIP1
TNS4
TRIM14
TRIM23
TRIM29
TRIM42
TRIM54
TRIM62
TSGA10IP
TSNAX
UBE2I
UNKL
USH1G
USP15
USP2
VCPKMT
VPS28
YES1
ZBTB16
ZC2HC1C
ZCCHC7
ZGPAT
ZMYM5
ZNF121
ZNF19
ZNF20
ZNF250
ZNF417
ZNF426
ZNF572
ZNF587
ZNF620
ZNF655
ZNF688
ZNF774
ZNF829
ZRANB1
ZZZ3
Entrez ID
54764
64170
HPRD ID
11738
06236
Ensembl ID
ENSG00000019995
ENSG00000187796
Uniprot IDs
Q9UGI0
A0A024R8F1
Q9H257
PDB IDs
3ZRH
5AF6
6E25
6E26
6E27
6E28
6N2M
6N2P
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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