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CARD9 and KRT40
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
484
Data Source:
BioGRID
(two hybrid)
CARD9
KRT40
Description
caspase recruitment domain family member 9
keratin 40
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Plasma Membrane
CBM Complex
Protein-containing Complex
Cytosol
Intermediate Filament
Molecular Function
Protein Binding
Protein Homodimerization Activity
Protein Self-association
Metal Ion Binding
CARD Domain Binding
Structural Molecule Activity
Protein Binding
Biological Process
Positive Regulation Of Cytokine Production
Neutrophil Mediated Immunity
I-kappaB Kinase/NF-kappaB Signaling
Response To Xenobiotic Stimulus
Immunoglobulin Mediated Immune Response
Response To Peptidoglycan
Response To Muramyl Dipeptide
Regulation Of Interleukin-2 Production
Positive Regulation Of Chemokine Production
Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Production
Positive Regulation Of Interleukin-17 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Stress-activated MAPK Cascade
Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Exogenous DsRNA
Positive Regulation Of Innate Immune Response
Positive Regulation Of JNK Cascade
Host-mediated Regulation Of Intestinal Microbiota Composition
Defense Response To Gram-positive Bacterium
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Homooligomerization
Defense Response To Virus
Antifungal Innate Immune Response
Positive Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of T-helper 17 Type Immune Response
Pathways
NOD1/2 Signaling Pathway
CLEC7A (Dectin-1) signaling
Keratinization
Formation of the cornified envelope
Drugs
Diseases
GWAS
Acute insulin response (insulin secretion adjusted) (
28490609
)
Ankylosing spondylitis (
23749187
21743469
)
Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) (
26974007
)
Crohn's disease (
28067908
22936669
21102463
)
Hip circumference adjusted for BMI (
34021172
)
IgA nephropathy (
25305756
)
Inflammatory bowel disease (
28067908
23128233
)
Joint damage in rheumatoid arthritis (
26498133
)
Large artery stroke (
28265093
)
Monocyte chemoattractant protein-1 levels (
23017229
)
Obesity-related traits (
23251661
)
Pediatric autoimmune diseases (
26301688
)
Takayasu arteritis (
33308445
)
Ulcerative colitis (
19915572
28067908
20228799
21297633
)
Gut microbiota (bacterial taxa, rank normal transformation method) (
32572223
)
Interacting Genes
138 interacting genes:
ABLIM1
AMOTL2
AXIN1
BCL10
BLZF1
C1orf94
C2CD6
CABP2
CARD10
CBX8
CCDC13
CCDC136
CCDC85B
CCDC88B
CCHCR1
CDC37
CDCA7L
CDK2AP1
CEP57L1
CEP70
CSNK2A1
CWF19L2
DAXX
DISC1
DUSP13
DVL2
EFHC2
EIF4A3
EIF4E2
FAM124B
FAM161A
FAM161B
FAM50B
FAM90A1
FOXD4L1
GAS8
GEM
HMBOX1
HOXB5
HSF2BP
IHO1
IKZF3
INO80B
IQCE
KANK2
KCTD9
KIAA0408
KIAA1328
KIF9
KIFC3
KRT15
KRT16
KRT19
KRT31
KRT40
KRT75
KRTAP10-1
KRTAP10-3
KRTAP10-5
KRTAP5-7
L3MBTL2
LENG1
LMO1
LMO3
LNX1
LZTS1
LZTS2
MCRS1
MEOX2
MFAP1
MID2
MYO15B
NECAB2
NTAQ1
PAK5
PBX2
PHC2
PIBF1
PICK1
PKP2
PNMA5
PPP1R18
PRPF18
PSMA4
RBAK
RTP5
SAXO1
SCNM1
SHISA6
SLAIN1
SSX2IP
STMN3
STX11
SUMO1
TASOR2
TCEANC
TCL1A
TEX33
TFIP11
TLE5
TNFAIP1
TNS4
TRIM14
TRIM23
TRIM29
TRIM42
TRIM54
TRIM62
TSGA10IP
TSNAX
UBE2I
UNKL
USH1G
USP15
USP2
VCPKMT
VPS28
YES1
ZBTB16
ZC2HC1C
ZCCHC7
ZGPAT
ZMYM5
ZNF121
ZNF19
ZNF20
ZNF250
ZNF417
ZNF426
ZNF572
ZNF587
ZNF620
ZNF655
ZNF688
ZNF774
ZNF829
ZRANB1
ZZZ3
381 interacting genes:
ACSF3
ADAMTS1
ADAMTSL3
AEN
AGXT
AKAP17A
ALDH3B1
ANKRD36BP1
AP1M1
AQP1
AQP5
ARID5A
ARMC7
ARSI
ASMTL
ATPAF2
AVPI1
AXIN1
BAHD1
BARD1
BCAS2
BEX2
BMS1P1
BRME1
BYSL
C10orf62
C11orf87
C19orf73
C1orf109
C1orf216
C22orf46
C2CD6
C2orf68
C4orf45
C5orf60
C6orf226
C8orf48
CA6
CARD9
CATIP
CBX8
CCDC112
CCDC116
CCDC120
CCDC146
CCDC185
CCDC198
CCDC26
CCDC93
CCER1
CCHCR1
CCNG1
CD33
CDC20B
CDK18
CDK5R1
CELA2B
CEP57
CEP57L1
CFAP206
CHCHD2
CHCHD3
CHIC2
CLEC18A
CNNM3
CNTF
COL8A1
COMT
COX5A
CREB5
CRY2
CTSZ
CWF19L2
CYCS
CYTH4
DAAM2
DCDC2B
DCX
DDX6
DHX57
DLGAP2
DMRT3
DOCK2
DOCK8
DTNB
EIF4E2
ELOA
ENKD1
EXOC3-AS1
FADS2
FAM107A
FAM124B
FAM214A
FAM27E3
FAM71C
FAM74A4
FAM90A1
FARS2
FASLG
FBF1
FBXL18
FBXO34
FBXW5
FEZF1
FKBP1B
FNDC11
FOXB1
FRG1
GAD1
GADD45GIP1
GATA2
GATAD2A
GEM
GFOD1
GGN
GLIDR
GNAI2
GNE
GNG5
GOLGA6L2
GPATCH2L
GTF3C5
GUCD1
HAPLN2
HAUS1
HBA2
HBZ
HCK
HDAC4
HGS
HNRNPLL
HOXA1
HOXB9
HOXC8
HSD3B7
HSF4
HSPA12B
HSPD1
ING5
INO80B
INPP5D
IQUB
ISCU
ITGB4
ITGB5
JOSD1
KANK2
KAT5
KCTD9
KDM1A
KIFC3
KLHL38
KPNA2
KRT2
KRT20
KRT4
KRT5
KRT6A
KRT6B
KRT6C
KRT71
KRT72
KRT75
KRT76
KRT8
KRT81
KRT82
KRT83
KRT85
KRT86
LAGE3
LCE3E
LENG1
LHX4
LIMS2
LIN37
LINC00636
LINC01588
LMF2
LMO1
LMO2
LMO4
LRCH4
MAB21L2
MAGOHB
MAPKBP1
MARK4
MED8
METTL17
MFAP1
MID2
MOB3C
MOBP
MOS
MRPL11
MRRF
MSRB3
MTA1
MXI1
MYPOP
NAB2
NAPRT
NDEL1
NEK6
NFKBID
NINJ1
NOL4L-DT
NPBWR2
NPPB
NR1D2
NXF1
ODAD4
OIP5
OPCML
OTUB2
PDLIM5
PGLS
PHF1
PHF21A
PHLDA1
PIGS
PIMREG
PIN1
PKD2
POLDIP3
POLL
POM121L8P
POP5
PPP1R18
PRAM1
PRKAA1
PRKAB2
PRPF18
PRPF31
PSMA1
PSMB1
PSMC5
PTGER3
PTPMT1
PXMP2
QPRT
RAB3IL1
RAB3IP
RAC1
RASSF5
RBM41
RCOR3
RECK
RGS8
RNF213
RNF6
RPL11
RSPH14
RTP5
RWDD2B
RXRB
SCAND1
SCOC
SEMA4C
SETD5
SH2D4A
SHC3
SHFL
SIRPA
SLC23A1
SLC25A10
SLIRP
SLU7
SMARCE1
SMCO4
SNAI1
SNHG11
SNRPB
SNW1
SPATA24
SPATC1L
SPEF1
SPG7
SRSF2
SSX2
SSX2IP
SUOX
SYT6
TACO1
TAPBPL
TBC1D16
TBC1D21
TBC1D22B
TCEA2
TCEANC
TCHP
TEAD4
THAP7
TIE1
TLE5
TMEM231
TMEM241
TMSB4X
TNIP3
TNNT1
TRAF4
TRIM42
TROAP
TRPV6
TSC22D4
TSGA10IP
TSHZ3
TTC23
TTC9C
TTLL10
TXLNA
TXN2
TXNDC5
TYK2
TYRO3
UACA
UBASH3A
UCMA
USHBP1
USP2
USP21
UTP14C
UTP23
UXT
VEZF1
WDR25
WT1
WT1-AS
ZBTB16
ZBTB24
ZBTB38
ZBTB42
ZC2HC1C
ZFHX3
ZFP1
ZFP2
ZFP69B
ZFYVE21
ZFYVE26
ZGPAT
ZMAT2
ZNF101
ZNF124
ZNF138
ZNF165
ZNF17
ZNF20
ZNF202
ZNF230
ZNF250
ZNF26
ZNF266
ZNF286A
ZNF317
ZNF319
ZNF329
ZNF337
ZNF408
ZNF410
ZNF417
ZNF438
ZNF439
ZNF446
ZNF488
ZNF490
ZNF564
ZNF569
ZNF575
ZNF580
ZNF581
ZNF587
ZNF625
ZNF655
ZNF688
ZNF697
ZNF702P
ZNF76
ZNF792
ZNF844
ZNRF2P1
ZSCAN21
Entrez ID
64170
125115
HPRD ID
06236
08304
Ensembl ID
ENSG00000187796
ENSG00000204889
Uniprot IDs
A0A024R8F1
Q9H257
Q6A162
PDB IDs
6E25
6E26
6E27
6E28
6N2M
6N2P
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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