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CARD9 and TSGA10IP
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
86
Data Source:
BioGRID
(two hybrid)
CARD9
TSGA10IP
Description
caspase recruitment domain family member 9
testis specific 10 interacting protein
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Plasma Membrane
CBM Complex
Protein-containing Complex
Cilium
Photoreceptor Connecting Cilium
Ciliary Basal Body
Molecular Function
Protein Binding
Protein Homodimerization Activity
Protein Self-association
Metal Ion Binding
CARD Domain Binding
Protein Binding
Biological Process
Positive Regulation Of Cytokine Production
Neutrophil Mediated Immunity
I-kappaB Kinase/NF-kappaB Signaling
Response To Xenobiotic Stimulus
Immunoglobulin Mediated Immune Response
Response To Peptidoglycan
Response To Muramyl Dipeptide
Regulation Of Interleukin-2 Production
Positive Regulation Of Chemokine Production
Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Production
Positive Regulation Of Interleukin-17 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Stress-activated MAPK Cascade
Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Exogenous DsRNA
Positive Regulation Of Innate Immune Response
Positive Regulation Of JNK Cascade
Host-mediated Regulation Of Intestinal Microbiota Composition
Defense Response To Gram-positive Bacterium
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Homooligomerization
Defense Response To Virus
Antifungal Innate Immune Response
Positive Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of T-helper 17 Type Immune Response
Cilium Organization
Pathways
NOD1/2 Signaling Pathway
CLEC7A (Dectin-1) signaling
Drugs
Diseases
GWAS
Acute insulin response (insulin secretion adjusted) (
28490609
)
Ankylosing spondylitis (
23749187
21743469
)
Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) (
26974007
)
Crohn's disease (
28067908
22936669
21102463
)
Hip circumference adjusted for BMI (
34021172
)
IgA nephropathy (
25305756
)
Inflammatory bowel disease (
28067908
23128233
)
Joint damage in rheumatoid arthritis (
26498133
)
Large artery stroke (
28265093
)
Monocyte chemoattractant protein-1 levels (
23017229
)
Obesity-related traits (
23251661
)
Pediatric autoimmune diseases (
26301688
)
Takayasu arteritis (
33308445
)
Ulcerative colitis (
19915572
28067908
20228799
21297633
)
Acne (severe) (
24927181
)
Body fat distribution (leg fat ratio) (
30664634
)
Body fat distribution (trunk fat ratio) (
30664634
)
Severe influenza A (H1N1) infection (
26379185
)
Urate levels (
31578528
)
Interacting Genes
138 interacting genes:
ABLIM1
AMOTL2
AXIN1
BCL10
BLZF1
C1orf94
C2CD6
CABP2
CARD10
CBX8
CCDC13
CCDC136
CCDC85B
CCDC88B
CCHCR1
CDC37
CDCA7L
CDK2AP1
CEP57L1
CEP70
CSNK2A1
CWF19L2
DAXX
DISC1
DUSP13
DVL2
EFHC2
EIF4A3
EIF4E2
FAM124B
FAM161A
FAM161B
FAM50B
FAM90A1
FOXD4L1
GAS8
GEM
HMBOX1
HOXB5
HSF2BP
IHO1
IKZF3
INO80B
IQCE
KANK2
KCTD9
KIAA0408
KIAA1328
KIF9
KIFC3
KRT15
KRT16
KRT19
KRT31
KRT40
KRT75
KRTAP10-1
KRTAP10-3
KRTAP10-5
KRTAP5-7
L3MBTL2
LENG1
LMO1
LMO3
LNX1
LZTS1
LZTS2
MCRS1
MEOX2
MFAP1
MID2
MYO15B
NECAB2
NTAQ1
PAK5
PBX2
PHC2
PIBF1
PICK1
PKP2
PNMA5
PPP1R18
PRPF18
PSMA4
RBAK
RTP5
SAXO1
SCNM1
SHISA6
SLAIN1
SSX2IP
STMN3
STX11
SUMO1
TASOR2
TCEANC
TCL1A
TEX33
TFIP11
TLE5
TNFAIP1
TNS4
TRIM14
TRIM23
TRIM29
TRIM42
TRIM54
TRIM62
TSGA10IP
TSNAX
UBE2I
UNKL
USH1G
USP15
USP2
VCPKMT
VPS28
YES1
ZBTB16
ZC2HC1C
ZCCHC7
ZGPAT
ZMYM5
ZNF121
ZNF19
ZNF20
ZNF250
ZNF417
ZNF426
ZNF572
ZNF587
ZNF620
ZNF655
ZNF688
ZNF774
ZNF829
ZRANB1
ZZZ3
113 interacting genes:
AKAP8L
AMOTL2
AP1B1
ARHGEF9
BHLHB9
BICD2
BICDL2
BIRC7
BRCA1
C1orf109
CALCOCO2
CARD9
CAVIN1
CBY2
CCDC102B
CCDC120
CCDC125
CCDC13
CCDC136
CCDC57
CCDC88B
CDKN2D
CDR2
CDR2L
CEP63
CEP70
CIB1
CRACR2B
CTAG1A
CTAG1B
CYSRT1
DMAP1
DYDC1
EFHC1
FCHSD2
FHL3
FRS3
FSD2
GAS8
GOLGA2
GOLGA6A
GOLGA6L9
GRIPAP1
HMBOX1
HOMEZ
HOOK2
HSF2BP
IKZF3
JAKMIP1
KANK2
KHDRBS3
KIFC3
KRT24
KRT36
KRT40
KRT86
KRTAP12-2
KRTAP6-2
LCA5L
LDOC1
LIPE
LMNB2
LMO2
LZTS1
MAGED1
MAP3K11
MBD3L1
MDFI
MEIS3
MEOX2
MIPOL1
MIS18A
MKRN3
MSS51
MTUS2
NAB2
NCOA5
NUTM1
PARVG
PDLIM7
PICK1
PRDM6
PRKAR1B
PSTPIP1
RASGEF1B
RBM4B
RBPMS
ROPN1
RORB
RUNDC3A
SAAL1
SORBS3
SPG21
SSX2IP
STX11
STX1A
TBC1D1
TEKT1
TFIP11
TLE5
TRAF2
TRAF4
TRIM27
TRIM5
TRIM50
TRIP6
TSC1
TTC23
TTC23L
UHMK1
WWOX
YES1
ZRANB1
Entrez ID
64170
254187
HPRD ID
06236
08147
Ensembl ID
ENSG00000187796
ENSG00000175513
Uniprot IDs
A0A024R8F1
Q9H257
Q3SY00
PDB IDs
6E25
6E26
6E27
6E28
6N2M
6N2P
Enriched GO Terms of Interacting Partners
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