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CARD9 and ZBTB16
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
86
Data Source:
BioGRID
(two hybrid)
CARD9
ZBTB16
Description
caspase recruitment domain family member 9
zinc finger and BTB domain containing 16
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Plasma Membrane
CBM Complex
Protein-containing Complex
Nucleus
Cytosol
Plasma Membrane
Nuclear Body
PML Body
Nuclear Speck
Transcription Repressor Complex
Protein-containing Complex
Molecular Function
Protein Binding
Protein Homodimerization Activity
Protein Self-association
Metal Ion Binding
CARD Domain Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Transcription Corepressor Binding
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Protein Binding
Protein C-terminus Binding
Protein Domain Specific Binding
Identical Protein Binding
Protein Homodimerization Activity
Metal Ion Binding
Biological Process
Positive Regulation Of Cytokine Production
Neutrophil Mediated Immunity
I-kappaB Kinase/NF-kappaB Signaling
Response To Xenobiotic Stimulus
Immunoglobulin Mediated Immune Response
Response To Peptidoglycan
Response To Muramyl Dipeptide
Regulation Of Interleukin-2 Production
Positive Regulation Of Chemokine Production
Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Production
Positive Regulation Of Interleukin-17 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Stress-activated MAPK Cascade
Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Exogenous DsRNA
Positive Regulation Of Innate Immune Response
Positive Regulation Of JNK Cascade
Host-mediated Regulation Of Intestinal Microbiota Composition
Defense Response To Gram-positive Bacterium
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Homooligomerization
Defense Response To Virus
Antifungal Innate Immune Response
Positive Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of T-helper 17 Type Immune Response
Negative Regulation Of Transcription By RNA Polymerase II
Mesonephros Development
Regulation Of Transcription By RNA Polymerase II
Apoptotic Process
Central Nervous System Development
Negative Regulation Of Cell Population Proliferation
Embryonic Pattern Specification
Anterior/posterior Pattern Specification
Protein Ubiquitination
Hemopoiesis
Myeloid Cell Differentiation
Positive Regulation Of Chondrocyte Differentiation
Protein Localization To Nucleus
Embryonic Hindlimb Morphogenesis
Forelimb Morphogenesis
Embryonic Digit Morphogenesis
Positive Regulation Of Apoptotic Process
Ossification Involved In Bone Maturation
Positive Regulation Of Fat Cell Differentiation
Negative Regulation Of Myeloid Cell Differentiation
Positive Regulation Of Ossification
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Male Germ-line Stem Cell Asymmetric Division
Positive Regulation Of NK T Cell Differentiation
Cartilage Development
Positive Regulation Of Cartilage Development
Pathways
NOD1/2 Signaling Pathway
CLEC7A (Dectin-1) signaling
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Acute insulin response (insulin secretion adjusted) (
28490609
)
Ankylosing spondylitis (
23749187
21743469
)
Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) (
26974007
)
Crohn's disease (
28067908
22936669
21102463
)
Hip circumference adjusted for BMI (
34021172
)
IgA nephropathy (
25305756
)
Inflammatory bowel disease (
28067908
23128233
)
Joint damage in rheumatoid arthritis (
26498133
)
Large artery stroke (
28265093
)
Monocyte chemoattractant protein-1 levels (
23017229
)
Obesity-related traits (
23251661
)
Pediatric autoimmune diseases (
26301688
)
Takayasu arteritis (
33308445
)
Ulcerative colitis (
19915572
28067908
20228799
21297633
)
Basophil count (
32888494
)
Chronotype (
30696823
)
Conduct disorder (maternal expressed emotions interaction) (
18846501
)
Corneal astigmatism (
29422769
)
Diisocyanate-induced asthma (
25918132
)
Granulocyte count (
27863252
)
Granulocyte percentage of myeloid white cells (
27863252
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Mean platelet volume (
32888494
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Monocyte count (
32888494
)
Monocyte percentage of white cells (
32888494
27863252
)
Myeloid white cell count (
27863252
)
Neutrophil count (
32888494
27863252
)
Neutrophil percentage of white cells (
32888494
)
Non-glioblastoma glioma (
28346443
26424050
)
Paneth cell defects in Crohn's disease (
28352666
)
Platelet count (
32888494
27863252
)
Plateletcrit (
32888494
27863252
)
Polycystic ovary syndrome (
26284813
30566500
)
Red blood cell count (
32888494
)
Smoking initiation (
33082346
)
Sum basophil neutrophil counts (
27863252
)
Sum neutrophil eosinophil counts (
27863252
)
Urinary albumin-to-creatinine ratio (
32600054
)
White blood cell count (
32888494
27863252
)
Interacting Genes
138 interacting genes:
ABLIM1
AMOTL2
AXIN1
BCL10
BLZF1
C1orf94
C2CD6
CABP2
CARD10
CBX8
CCDC13
CCDC136
CCDC85B
CCDC88B
CCHCR1
CDC37
CDCA7L
CDK2AP1
CEP57L1
CEP70
CSNK2A1
CWF19L2
DAXX
DISC1
DUSP13
DVL2
EFHC2
EIF4A3
EIF4E2
FAM124B
FAM161A
FAM161B
FAM50B
FAM90A1
FOXD4L1
GAS8
GEM
HMBOX1
HOXB5
HSF2BP
IHO1
IKZF3
INO80B
IQCE
KANK2
KCTD9
KIAA0408
KIAA1328
KIF9
KIFC3
KRT15
KRT16
KRT19
KRT31
KRT40
KRT75
KRTAP10-1
KRTAP10-3
KRTAP10-5
KRTAP5-7
L3MBTL2
LENG1
LMO1
LMO3
LNX1
LZTS1
LZTS2
MCRS1
MEOX2
MFAP1
MID2
MYO15B
NECAB2
NTAQ1
PAK5
PBX2
PHC2
PIBF1
PICK1
PKP2
PNMA5
PPP1R18
PRPF18
PSMA4
RBAK
RTP5
SAXO1
SCNM1
SHISA6
SLAIN1
SSX2IP
STMN3
STX11
SUMO1
TASOR2
TCEANC
TCL1A
TEX33
TFIP11
TLE5
TNFAIP1
TNS4
TRIM14
TRIM23
TRIM29
TRIM42
TRIM54
TRIM62
TSGA10IP
TSNAX
UBE2I
UNKL
USH1G
USP15
USP2
VCPKMT
VPS28
YES1
ZBTB16
ZC2HC1C
ZCCHC7
ZGPAT
ZMYM5
ZNF121
ZNF19
ZNF20
ZNF250
ZNF417
ZNF426
ZNF572
ZNF587
ZNF620
ZNF655
ZNF688
ZNF774
ZNF829
ZRANB1
ZZZ3
154 interacting genes:
ACP5
ADAMTS4
AGTR2
AMOTL2
ANAPC5
ANXA7
AR
ATP6AP2
ATP7B
BCL6
BLZF1
BMI1
CARD9
CASP3
CCDC85B
CCHCR1
CD81
CDK1
CDK4
CDKN1A
CEBPA
CEP70
CEP72
CFH
CIDEA
COG6
COQ6
CTDSP1
DLST
DNAAF5
DNM2
DPM1
EEF1A1
EFHC2
EIF2S2
ENOX1
EP300
EPN1
ERVK-6
ESR1
FAM217B
FAM90A1
FCHO1
FHL2
FHL5
FSHR
GATA1
GATA2
GCSH
GNE
GOLGA2
GOLGA6L9
GPANK1
GRB7
GSTM4
HBEGF
HDAC1
HDAC2
HDAC3
HDAC4
HDAC5
HDAC6
HDAC7
HDAC9
HDX
HOXA1
HOXC5
HSF2BP
ICAM3
IL6
KIAA1549
KIFC3
KRT40
KRTAP4-12
LAMTOR5
LDOC1
LMTK3
LRIG1
LSM2
LYAR
MAGEA11
MAP3K3
MCUB
MEOX2
MID2
MTUS2
MX1
MYLIP
NCOR1
NCOR2
NFKBID
NME4
NR3C1
OSBPL3
PAFAH1B3
PARP1
PGAM5
PHF1
PIAS2
PIBF1
PLSCR1
PMAIP1
PML
PNRC2
PRKAR1B
PSMD11
PSMD2
QTRT1
RAB27A
RAB3IP
RARA
RB1
REL
RFLNB
RINT1
RUNX1T1
RXRA
SH2D4A
SIN3A
SIN3B
SMAD3
SMN1
SP1
SPOP
SPRY2
SUMO1
TAB2
TERF1
THNSL2
TK1
TLE5
TOLLIP
TRAF1
TRAF2
TRAF4
TRIM21
TRIM23
TRIM27
TRIM54
TTC23
TXNIP
UBE2I
VDR
VTA1
WASHC1
WDR33
YJU2B
ZBTB32
ZBTB42
ZNF24
ZNF281
ZNF552
ZNF620
ZNF655
Entrez ID
64170
7704
HPRD ID
06236
11762
Ensembl ID
ENSG00000187796
ENSG00000109906
Uniprot IDs
A0A024R8F1
Q9H257
A0A024R3C6
Q05516
PDB IDs
6E25
6E26
6E27
6E28
6N2M
6N2P
1BUO
1CS3
Enriched GO Terms of Interacting Partners
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