CHRAC1 and POLE3

Number of citations of the paper that reports this interaction (PubMedID 10880450)
73

Data Source:
HPRD (in vivo)

		CHRAC1	POLE3
Description		chromatin accessibility complex subunit 1	DNA polymerase epsilon 3, accessory subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Epsilon DNA Polymerase Complex CHRAC	Nucleus Nucleoplasm Epsilon DNA Polymerase Complex CHRAC
	Molecular Function	DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Protein Heterodimerization Activity	DNA-directed DNA Polymerase Activity Protein Binding Chromatin DNA Binding Protein Heterodimerization Activity
	Biological Process	Chromatin Remodeling DNA Biosynthetic Process	DNA Replication Leading Strand Elongation Cellular Response To DNA Damage Stimulus Heterochromatin Assembly Nucleosome Mobilization Histone H3 Acetylation DNA Biosynthetic Process
Pathways			Recognition of DNA damage by PCNA-containing replication complex PCNA-Dependent Long Patch Base Excision Repair Termination of translesion DNA synthesis HDR through Homologous Recombination (HRR) Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER DNA replication initiation Activation of the pre-replicative complex
Drugs			Cladribine
Diseases
GWAS		Experiencing mood swings ( 29500382)
Interacting Genes		5 interacting genes: APP BAZ1A FAM9B POLE3 SMARCA5	14 interacting genes: ALAD APP ASTN2 BAZ1A CHRAC1 CST3 DR1 DRAP1 EIF4G2 GSN POLE4 SMARCA5 TNC TRIM32
Entrez ID		54108	54107
HPRD ID		06275	06274
Ensembl ID		ENSG00000104472	ENSG00000148229
Uniprot IDs		Q9NRG0	A0A024R829 Q9NRF9
PDB IDs
Enriched GO Terms of Interacting Partners?
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