MIP and ATP6V0B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MIP	ATP6V0B
Description		major intrinsic protein of lens fiber	ATPase H+ transporting V0 subunit b
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Gap Junction Integral Component Of Membrane Apical Plasma Membrane	Lysosomal Membrane Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Calmodulin Binding Water Channel Activity	Transporter Activity Protein Binding Proton Transmembrane Transporter Activity
	Biological Process	Water Transport Visual Perception Positive Regulation Of Cell Adhesion Response To Stimulus Protein Homotetramerization Transmembrane Transport Gap Junction-mediated Intercellular Transport	Regulation Of Macroautophagy Proton Transmembrane Transport
Pathways		Passive transport by Aquaporins	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		B-nonylglucoside	Tiludronic acid
Diseases
GWAS		Apolipoprotein A1 levels ( 33730874) Axial length ( 24144296) Serum metabolite levels ( 33031748)	Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		47 interacting genes: AQP9 ATP6V0B CALM1 CD40 CISD2 CLDN5 CRYAA CRYAB CRYBB2 CRYGC ERGIC3 ERVFRD-1 FAM209A FCGR2A FOXA2 GJA3 GJA8 GJB5 GOLM1 GPX8 KCNJ6 LHFPL5 LMNA LRRC4C MFF MGST3 MRM3 MRPS18B MUC1 PDZK1IP1 PRKACA RELL2 SAR1A SGPL1 SLC14A1 SLC18A1 SSMEM1 STX1A STX2 SYAP1 SYT1 SYT2 TMEM139 TMEM154 TMEM52B TMX2 ZFPL1	34 interacting genes: ADGRG3 ADRB2 APOD BPI CCL19 COL4A5 DAPK2 EMP1 FAM210B FAS GJA8 GPR42 GPR61 INSIG2 IRAK3 KLRC1 MFF MIP MS4A3 MTNR1B NRM RPS26P15 SLC10A1 SLC2A5 SNTA1 SPACA1 STOM TM4SF19 TMEM242 TTC39A VMA21 YWHAE YWHAG ZFYVE9
Entrez ID		4284	533
HPRD ID		01098	04759
Ensembl ID		ENSG00000135517	ENSG00000117410
Uniprot IDs		P30301	E9PNL3 Q99437
PDB IDs			6WLW 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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