MIP and SSMEM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MIP	SSMEM1
Description		major intrinsic protein of lens fiber	serine rich single-pass membrane protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Gap Junction Integral Component Of Membrane Apical Plasma Membrane	Integral Component Of Membrane
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Calmodulin Binding Water Channel Activity	Protein Binding
	Biological Process	Water Transport Visual Perception Positive Regulation Of Cell Adhesion Response To Stimulus Protein Homotetramerization Transmembrane Transport Gap Junction-mediated Intercellular Transport
Pathways		Passive transport by Aquaporins
Drugs		B-nonylglucoside
Diseases
GWAS		Apolipoprotein A1 levels ( 33730874) Axial length ( 24144296) Serum metabolite levels ( 33031748)	Neurological blood protein biomarker levels ( 31320639)
Interacting Genes		47 interacting genes: AQP9 ATP6V0B CALM1 CD40 CISD2 CLDN5 CRYAA CRYAB CRYBB2 CRYGC ERGIC3 ERVFRD-1 FAM209A FCGR2A FOXA2 GJA3 GJA8 GJB5 GOLM1 GPX8 KCNJ6 LHFPL5 LMNA LRRC4C MFF MGST3 MRM3 MRPS18B MUC1 PDZK1IP1 PRKACA RELL2 SAR1A SGPL1 SLC14A1 SLC18A1 SSMEM1 STX1A STX2 SYAP1 SYT1 SYT2 TMEM139 TMEM154 TMEM52B TMX2 ZFPL1	95 interacting genes: ALG3 APOA2 AQP1 AQP10 AQP3 ATP6V0C BET1 BLCAP C11orf24 C1QL4 C4orf3 C5 CCL4L2 CDS2 CLRN2 CMTM7 CSGALNACT2 CTSA CXCL16 CXCL9 CYB561 CYBC1 DEFB103A DEFB103B DEFB121 EFNA5 EMD ERG28 ERMP1 FAM3C FATE1 FDPS FPR2 GJB2 GPHB5 GPR151 HMOX2 LAT LEPROTL1 LNPEP MARCHF2 MCRS1 MFSD12 MFSD5 MFSD6 MIP MMD2 MS4A13 NIPAL4 NRM PGAP2 PLPP1 PLPP4 PLPP6 PLPPR2 RHD RTP2 RUSF1 S1PR5 SERP1 SLC35A1 SLC35C2 SLC35E3 SLC38A1 SLC38A7 SLC39A2 SLC39A9 SLC41A1 SLC41A2 STX8 TAP1 TAS2R10 TLCD1 TM6SF2 TMEM128 TMEM14A TMEM14C TMEM203 TMEM218 TMEM222 TMEM239 TMEM243 TMEM45A TMEM60 TMEM86A TMEM86B TMEM97 TMPPE TNF TRARG1 UNC93B1 UPK1B VAMP4 YIPF6 ZFPL1
Entrez ID		4284	136263
HPRD ID		01098	14060
Ensembl ID		ENSG00000135517	ENSG00000165120
Uniprot IDs		P30301	A0A3B3ISA2 A4D1L0 Q8WWF3
PDB IDs
Enriched GO Terms of Interacting Partners?
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