MIP and ERVFRD-1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MIP	ERVFRD-1
Description		major intrinsic protein of lens fiber	endogenous retrovirus group FRD member 1, envelope
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Gap Junction Integral Component Of Membrane Apical Plasma Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Calmodulin Binding Water Channel Activity	Protein Binding
	Biological Process	Water Transport Visual Perception Positive Regulation Of Cell Adhesion Response To Stimulus Protein Homotetramerization Transmembrane Transport Gap Junction-mediated Intercellular Transport	Syncytium Formation By Plasma Membrane Fusion Syncytium Formation Myoblast Fusion
Pathways		Passive transport by Aquaporins
Drugs		B-nonylglucoside
Diseases
GWAS		Apolipoprotein A1 levels ( 33730874) Axial length ( 24144296) Serum metabolite levels ( 33031748)
Interacting Genes		47 interacting genes: AQP9 ATP6V0B CALM1 CD40 CISD2 CLDN5 CRYAA CRYAB CRYBB2 CRYGC ERGIC3 ERVFRD-1 FAM209A FCGR2A FOXA2 GJA3 GJA8 GJB5 GOLM1 GPX8 KCNJ6 LHFPL5 LMNA LRRC4C MFF MGST3 MRM3 MRPS18B MUC1 PDZK1IP1 PRKACA RELL2 SAR1A SGPL1 SLC14A1 SLC18A1 SSMEM1 STX1A STX2 SYAP1 SYT1 SYT2 TMEM139 TMEM154 TMEM52B TMX2 ZFPL1	15 interacting genes: APP BCL2L2 CCL4L2 ERMP1 FXR1 GPHB5 MIP NINJ2 NXPE3 PAEP SEC22A SLC30A8 SLC41A2 TAP1 TMPRSS4
Entrez ID		4284	405754
HPRD ID		01098	13648
Ensembl ID		ENSG00000135517	ENSG00000244476
Uniprot IDs		P30301	P60508
PDB IDs			1Y4M 6RX3
Enriched GO Terms of Interacting Partners?
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