ERVFRD-1 and MIP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ERVFRD-1	MIP
Description		endogenous retrovirus group FRD member 1, envelope	major intrinsic protein of lens fiber
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Gap Junction Integral Component Of Membrane Apical Plasma Membrane
	Molecular Function	Protein Binding	Structural Constituent Of Eye Lens Protein Binding Calmodulin Binding Water Channel Activity
	Biological Process	Syncytium Formation By Plasma Membrane Fusion Syncytium Formation Myoblast Fusion	Water Transport Visual Perception Positive Regulation Of Cell Adhesion Response To Stimulus Protein Homotetramerization Transmembrane Transport Gap Junction-mediated Intercellular Transport
Pathways			Passive transport by Aquaporins
Drugs			B-nonylglucoside
Diseases
GWAS			Apolipoprotein A1 levels ( 33730874) Axial length ( 24144296) Serum metabolite levels ( 33031748)
Interacting Genes		15 interacting genes: APP BCL2L2 CCL4L2 ERMP1 FXR1 GPHB5 MIP NINJ2 NXPE3 PAEP SEC22A SLC30A8 SLC41A2 TAP1 TMPRSS4	47 interacting genes: AQP9 ATP6V0B CALM1 CD40 CISD2 CLDN5 CRYAA CRYAB CRYBB2 CRYGC ERGIC3 ERVFRD-1 FAM209A FCGR2A FOXA2 GJA3 GJA8 GJB5 GOLM1 GPX8 KCNJ6 LHFPL5 LMNA LRRC4C MFF MGST3 MRM3 MRPS18B MUC1 PDZK1IP1 PRKACA RELL2 SAR1A SGPL1 SLC14A1 SLC18A1 SSMEM1 STX1A STX2 SYAP1 SYT1 SYT2 TMEM139 TMEM154 TMEM52B TMX2 ZFPL1
Entrez ID		405754	4284
HPRD ID		13648	01098
Ensembl ID		ENSG00000244476	ENSG00000135517
Uniprot IDs		P60508	P30301
PDB IDs		1Y4M 6RX3
Enriched GO Terms of Interacting Partners?
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