SSMEM1 and PLPP6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SSMEM1	PLPP6
Description		serine rich single-pass membrane protein 1	phospholipid phosphatase 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding Hydrolase Activity Sphingosine-1-phosphate Phosphatase Activity Lipid Phosphatase Activity
	Biological Process		Cholesterol Biosynthetic Process Phospholipid Dephosphorylation
Pathways			Cholesterol biosynthesis
Drugs
Diseases
GWAS		Neurological blood protein biomarker levels ( 31320639)
Interacting Genes		95 interacting genes: ALG3 APOA2 AQP1 AQP10 AQP3 ATP6V0C BET1 BLCAP C11orf24 C1QL4 C4orf3 C5 CCL4L2 CDS2 CLRN2 CMTM7 CSGALNACT2 CTSA CXCL16 CXCL9 CYB561 CYBC1 DEFB103A DEFB103B DEFB121 EFNA5 EMD ERG28 ERMP1 FAM3C FATE1 FDPS FPR2 GJB2 GPHB5 GPR151 HMOX2 LAT LEPROTL1 LNPEP MARCHF2 MCRS1 MFSD12 MFSD5 MFSD6 MIP MMD2 MS4A13 NIPAL4 NRM PGAP2 PLPP1 PLPP4 PLPP6 PLPPR2 RHD RTP2 RUSF1 S1PR5 SERP1 SLC35A1 SLC35C2 SLC35E3 SLC38A1 SLC38A7 SLC39A2 SLC39A9 SLC41A1 SLC41A2 STX8 TAP1 TAS2R10 TLCD1 TM6SF2 TMEM128 TMEM14A TMEM14C TMEM203 TMEM218 TMEM222 TMEM239 TMEM243 TMEM45A TMEM60 TMEM86A TMEM86B TMEM97 TMPPE TNF TRARG1 UNC93B1 UPK1B VAMP4 YIPF6 ZFPL1	57 interacting genes: AMIGO1 AQP6 AQP8 BTN2A1 BTNL9 C16orf92 CD79A CIAO2A CLDN15 CLDN9 CLEC4M CLN5 COMT CREB3L1 EBP FAM174A FAM209A FAM210B FKBP7 FNDC9 FXYD3 GJB5 GKN1 GORAB GPX8 HSH2D IL10RA IL13RA2 KASH5 LAYN LDLRAD1 MMGT1 MS4A3 MUC1 NCR3LG1 PDGFRA PDZK1IP1 PHACTR3 PRLR PVR RETREG3 RNF170 RNF5 SEC11C SHISAL1 SIGLEC12 SLC7A14 SMAGP SOCS4 SSMEM1 STX1A SYNE4 SYNPR TMEM106C TMIE TNFRSF10D VSIR
Entrez ID		136263	403313
HPRD ID		14060	17397
Ensembl ID		ENSG00000165120	ENSG00000205808
Uniprot IDs		A0A3B3ISA2 A4D1L0 Q8WWF3	Q8IY26
PDB IDs
Enriched GO Terms of Interacting Partners?
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