KIT and PTPN6

  • Number of citations of the paper that reports this interaction (PubMedID 7684496)
  • 50
  • Data Source:
  • HPRD (in vivo, in vitro)

KIT

PTPN6

Description KIT proto-oncogene, receptor tyrosine kinase protein tyrosine phosphatase non-receptor type 6
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Mean corpuscular hemoglobin concentration ( 29403010)
  • Red blood cell fatty acid levels ( 25500335)
  • Refractive error ( 32231278)
Interacting Genes 93 interacting genes: ABL1 ABL2 BCAR3 BLK BLNK BTK CBL CBLB CD81 CD9 CISH CLTC CRK CRKL CSF1R CSF2RA CSF2RB DOK1 EPOR FES FGR FYN GRAP GRAP2 GRB10 GRB2 GRB7 HCK HSH2D IL7R ILKAP INPP5D JAK2 JAK3 KDR KITLG LCK LYN MATK MPDZ NCK1 NCK2 PIK3CG PIK3R1 PIK3R2 PIK3R3 PLCE1 PLCG1 PLCG2 PRKCA PRKCB PTK6 PTPN11 PTPN20 PTPN6 PTPRO PTPRU RASA1 SH2B2 SH2B3 SH2D1A SH2D1B SH2D2A SH2D3C SH3BP2 SHB SHC1 SHC2 SHC3 SHC4 SLA2 SOCS1 SOCS2 SOCS3 SOCS5 SOCS6 SPRED1 SPRED2 SRC STAP1 STAT1 STAT5A STAT5B STYX SYK TEC TNS1 TNS2 TNS3 TXK VAV3 YES1 ZAP70 115 interacting genes: AATK ABL1 ACTN1 ACTN4 BCR BLNK BTLA CAV1 CBL CCDC88A CD22 CD247 CD300LF CD33 CD5 CD72 CD79A CD79B CDK1 CEACAM1 CLEC4A CSF2RB CTNNB1 CTNND1 CUZD1 CXCR4 DOK1 EGFR EPOR ERBB2 ERBB3 ERBB4 ESR1 FAS FCGR2B FCRL3 FGFR4 FHL3 FLT3 GAB2 GHR GRB2 HOXA10 IFNAR1 IGF1R IL2RB IL4R IL6ST INSR IRS2 IRS4 JAK1 JAK2 JAK3 KDR KHDRBS1 KIR2DL3 KIR2DL5A KIT KLRA1P KLRB1 KLRC1 LAIR1 LAT LCK LCP2 LIFR LILRB2 LILRB4 LMTK2 LYN MPIG6B MS4A2 MYH9 NOS1 OLIG1 PAG1 PDGFRB PECAM1 PIK3R1 PILRA PILRB PLCG2 PRKCA PRKCD PTK2B PTK7 PTPN11 PTPRC ROR1 ROR2 ROS1 SHC1 SIGLEC10 SIGLEC11 SIGLEC12 SIRPA SLAMF6 SOS1 SPATA2 SRC SSTR2 STAT5B STAT6 SYK TFG TLR10 TMEM62 TNFRSF1A TRAF3 TRAF6 TREML1 TYK2 VAV1 ZAP70
Entrez ID 3815 5777
HPRD ID 01287 01475
Ensembl ID ENSG00000157404 ENSG00000111679
Uniprot IDs A0A0U2N547 P10721 P29350 Q53XS4
PDB IDs 1PKG 1QZJ 1QZK 1R01 1T45 1T46 2E9W 2EC8 2IUH 2VIF 3G0E 3G0F 4HVS 4K94 4K9E 4PGZ 4U0I 6GQJ 6GQK 6GQL 6GQM 6HH1 6ITT 6ITV 6KLA 6MOB 6XV9 6XVA 6XVB 1FPR 1GWZ 1X6C 2B3O 2RMX 2YU7 3PS5 4GRY 4GRZ 4GS0 4HJP 4HJQ 6SM5
Enriched GO Terms of Interacting Partners?
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