Description |
protein tyrosine phosphatase non-receptor type 6 |
BCR activator of RhoGEF and GTPase |
Image |
|
|
GO Annotations |
Cellular Component |
|
|
Molecular Function |
|
|
Biological Process |
|
|
Pathways |
|
|
Drugs |
|
|
Diseases |
|
|
GWAS |
- Mean corpuscular hemoglobin concentration ( 29403010)
- Red blood cell fatty acid levels ( 25500335)
- Refractive error ( 32231278)
|
|
Interacting Genes |
115 interacting genes:
AATK
ABL1
ACTN1
ACTN4
BCR
BLNK
BTLA
CAV1
CBL
CCDC88A
CD22
CD247
CD300LF
CD33
CD5
CD72
CD79A
CD79B
CDK1
CEACAM1
CLEC4A
CSF2RB
CTNNB1
CTNND1
CUZD1
CXCR4
DOK1
EGFR
EPOR
ERBB2
ERBB3
ERBB4
ESR1
FAS
FCGR2B
FCRL3
FGFR4
FHL3
FLT3
GAB2
GHR
GRB2
HOXA10
IFNAR1
IGF1R
IL2RB
IL4R
IL6ST
INSR
IRS2
IRS4
JAK1
JAK2
JAK3
KDR
KHDRBS1
KIR2DL3
KIR2DL5A
KIT
KLRA1P
KLRB1
KLRC1
LAIR1
LAT
LCK
LCP2
LIFR
LILRB2
LILRB4
LMTK2
LYN
MPIG6B
MS4A2
MYH9
NOS1
OLIG1
PAG1
PDGFRB
PECAM1
PIK3R1
PILRA
PILRB
PLCG2
PRKCA
PRKCD
PTK2B
PTK7
PTPN11
PTPRC
ROR1
ROR2
ROS1
SHC1
SIGLEC10
SIGLEC11
SIGLEC12
SIRPA
SLAMF6
SOS1
SPATA2
SRC
SSTR2
STAT5B
STAT6
SYK
TFG
TLR10
TMEM62
TNFRSF1A
TRAF3
TRAF6
TREML1
TYK2
VAV1
ZAP70
|
45 interacting genes:
ABL1
ABL2
AFDN
APBA3
BLK
CBL
CDC42
CRK
CRKL
DLG1
DOK1
ERCC3
FES
GRB10
GRB2
HCK
HNF1A
IGSF21
IRS1
JAK2
LNX1
MAP4K5
PLCG1
PTPN1
PTPN11
PTPN6
RAC1
RAD51
RASA1
RHOA
SFN
SHC1
SRC
STUB1
TP53
TSG101
UBC
UNC119
VAV1
YWHAB
YWHAE
YWHAG
YWHAH
YWHAQ
YWHAZ
|
Entrez ID |
5777 |
613 |
HPRD ID |
01475 |
01044 |
Ensembl ID |
ENSG00000111679
|
ENSG00000186716
|
Uniprot IDs |
P29350
Q53XS4
|
P11274
|
PDB IDs |
1FPR
1GWZ
1X6C
2B3O
2RMX
2YU7
3PS5
4GRY
4GRZ
4GS0
4HJP
4HJQ
6SM5
|
1K1F
2AIN
5N6R
5N7E
5OC7
|
Enriched GO Terms of Interacting Partners? |
|
|
Tagcloud ? |
|
|
Tagcloud (Difference) ? |
|
|
Tagcloud (Intersection) ? |
|