NHLRC1 and GYS1

Number of citations of the paper that reports this interaction (PubMedID 22578008)
7

Data Source:
BioGRID (pull down)

		NHLRC1	GYS1
Description		NHL repeat containing E3 ubiquitin protein ligase 1	glycogen synthase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Cytosol Perinuclear Region Of Cytoplasm	Cytoplasm Cytosol Membrane Inclusion Body
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Glycogen (starch) Synthase Activity Protein Binding Glucose Binding Protein Kinase Binding Glycogen Synthase Activity, Transferring Glucose-1-phosphate
	Biological Process	Protein Polyubiquitination Glycogen Biosynthetic Process Autophagy Regulation Of Gene Expression Positive Regulation Of Protein Ubiquitination Response To Endoplasmic Reticulum Stress Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Kinase Activity Regulation Of Protein Localization To Plasma Membrane	Glycogen Biosynthetic Process Heart Development
Pathways		Glycogen synthesis Myoclonic epilepsy of Lafora	Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage disease type XV (GYG1) Glycogen storage disease type 0 (muscle GYS1)
Drugs
Diseases
GWAS		Intrinsic epigenetic age acceleration ( 29374233)
Interacting Genes		8 interacting genes: AGL GYS1 NNAT PPP1R3C UBE2D1 UBE2D3 UBE2E1 UBE2H	43 interacting genes: AIMP2 APP BEND7 CCDC33 CDCA8 CLVS2 CRX CSNK2A1 EFHC2 FAM228A GSK3B GYG1 GYG2 HOXB6 HOXC8 IHO1 INCA1 KATNBL1 KLF1 KLF4 MAPKAPK5 MEOX1 NDUFB7 NHLRC1 PCYT1A PINX1 PLAGL2 PNMA5 PRKACA RBM48 SNIP1 SORBS3 SUMO2 TFAP2D TLE5 WASHC1 ZBTB33 ZNF212 ZNF326 ZNF474 ZNF552 ZNF620 ZNF774
Entrez ID		378884	2997
HPRD ID		06995	00721
Ensembl ID		ENSG00000187566	ENSG00000104812
Uniprot IDs		Q6VVB1	P13807
PDB IDs
Enriched GO Terms of Interacting Partners?
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