GYS1 and CLVS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GYS1	CLVS2
Description		glycogen synthase 1	clavesin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane Inclusion Body	Endosome Trans-Golgi Network Clathrin-coated Vesicle Early Endosome Membrane Trans-Golgi Network Membrane
	Molecular Function	Glycogen (starch) Synthase Activity Protein Binding Glucose Binding Protein Kinase Binding Glycogen Synthase Activity, Transferring Glucose-1-phosphate	Protein Binding Phosphatidylinositol-3,5-bisphosphate Binding Phosphatidylinositol Bisphosphate Binding
	Biological Process	Glycogen Biosynthetic Process Heart Development	Lysosome Organization
Pathways		Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage disease type XV (GYG1) Glycogen storage disease type 0 (muscle GYS1)	Lysosome Vesicle Biogenesis
Drugs
Diseases
GWAS			Refractive error ( 32231278) Triglyceride levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429)
Interacting Genes		43 interacting genes: AIMP2 APP BEND7 CCDC33 CDCA8 CLVS2 CRX CSNK2A1 EFHC2 FAM228A GSK3B GYG1 GYG2 HOXB6 HOXC8 IHO1 INCA1 KATNBL1 KLF1 KLF4 MAPKAPK5 MEOX1 NDUFB7 NHLRC1 PCYT1A PINX1 PLAGL2 PNMA5 PRKACA RBM48 SNIP1 SORBS3 SUMO2 TFAP2D TLE5 WASHC1 ZBTB33 ZNF212 ZNF326 ZNF474 ZNF552 ZNF620 ZNF774	17 interacting genes: EMSY FBXW2 FLAD1 GSTM3 GSTZ1 GYS1 KAZN MEOX2 MYH7 PAFAH1B2 PCYT2 PGAM2 PHETA2 S100A7 S100A7A TACC2 TBC1D32
Entrez ID		2997	134829
HPRD ID		00721	16666
Ensembl ID		ENSG00000104812	ENSG00000146352
Uniprot IDs		P13807	Q5SYC1
PDB IDs
Enriched GO Terms of Interacting Partners?
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