GYS1 and CDCA8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GYS1	CDCA8
Description		glycogen synthase 1	cell division cycle associated 8
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane Inclusion Body	Chromosome, Centromeric Region Nucleoplasm Nucleolus Cytosol Chromocenter Midbody Chromosome Passenger Complex Protein-containing Complex Intercellular Bridge Spindle Midzone
	Molecular Function	Glycogen (starch) Synthase Activity Protein Binding Glucose Binding Protein Kinase Binding Glycogen Synthase Activity, Transferring Glucose-1-phosphate	Protein Binding
	Biological Process	Glycogen Biosynthetic Process Heart Development	Mitotic Sister Chromatid Segregation Mitotic Metaphase Plate Congression Chromosome Organization Cell Division
Pathways		Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage disease type XV (GYG1) Glycogen storage disease type 0 (muscle GYS1)	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA replication proteins RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Axial length ( 24144296) Eyebrow thickness ( 26926045)
Interacting Genes		43 interacting genes: AIMP2 APP BEND7 CCDC33 CDCA8 CLVS2 CRX CSNK2A1 EFHC2 FAM228A GSK3B GYG1 GYG2 HOXB6 HOXC8 IHO1 INCA1 KATNBL1 KLF1 KLF4 MAPKAPK5 MEOX1 NDUFB7 NHLRC1 PCYT1A PINX1 PLAGL2 PNMA5 PRKACA RBM48 SNIP1 SORBS3 SUMO2 TFAP2D TLE5 WASHC1 ZBTB33 ZNF212 ZNF326 ZNF474 ZNF552 ZNF620 ZNF774	26 interacting genes: AURKB BIRC5 EMILIN1 FBXO17 GYS1 H3C14 HLA-DRB3 HMBOX1 INCENP MAPKAPK5 NEK3 NKAPD1 NTAQ1 PIAS2 PIH1D2 RANBP2 RPRD1B SENP3 SET SGO1 SGO2 SNAPC5 SPANXN2 TTK UBE2I ZNF277
Entrez ID		2997	55143
HPRD ID		00721	13017
Ensembl ID		ENSG00000104812	ENSG00000134690
Uniprot IDs		P13807	Q53HL2
PDB IDs			2KDD 2QFA 2RAW 2RAX 6YIE 6YIF 6YIH
Enriched GO Terms of Interacting Partners?
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