EHD4 and AFP

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		EHD4	AFP
Description		EH domain containing 4	alpha fetoprotein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Early Endosome Endoplasmic Reticulum Plasma Membrane Membrane Endocytic Vesicle Early Endosome Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome	Extracellular Space Cytoplasm Endoplasmic Reticulum Lumen
	Molecular Function	Nucleic Acid Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding Cadherin Binding	Fatty Acid Binding Protein Binding Zinc Ion Binding
	Biological Process	Endocytosis Pinocytosis Endosomal Transport Regulation Of Endocytosis Endocytic Recycling Positive Regulation Of Peptidyl-tyrosine Phosphorylation Protein Homooligomerization Cilium Assembly Cellular Response To Growth Factor Stimulus Protein Localization To Plasma Membrane	Ovulation From Ovarian Follicle Transport Progesterone Metabolic Process SMAD Protein Signal Transduction
Pathways			Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) Granulocyte count ( 27863252) Heel bone mineral density ( 30598549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Lymphocyte percentage of white cells ( 32888494 27863252) Monocyte count ( 29403010 32888494 27863252) Monocyte percentage of white cells ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252)	Blood protein levels ( 30072576) Prostate cancer ( 23535732) Tumor biomarkers ( 23300138)
Interacting Genes		4 interacting genes: AFP CDC42 RASGRF1 SUMO2	14 interacting genes: AP4S1 CASP3 CCR5 CREBBP EHD4 GNB1 MED27 PHB2 PIDD1 PSMB7 PTEN SGSM2 SIRT1 XIAP
Entrez ID		30844	174
HPRD ID		10435	00074
Ensembl ID		ENSG00000103966	ENSG00000081051
Uniprot IDs		A0A024R9N6 A8K9B9 Q9H223	P02771
PDB IDs			3MRK
Enriched GO Terms of Interacting Partners?
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