AFP and MED27

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		AFP	MED27
Description		alpha fetoprotein	mediator complex subunit 27
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Endoplasmic Reticulum Lumen	Ubiquitin Ligase Complex Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Cytosol Mediator Complex
	Molecular Function	Fatty Acid Binding Protein Binding Zinc Ion Binding	Transcription Coactivator Activity Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Ovulation From Ovarian Follicle Transport Progesterone Metabolic Process SMAD Protein Signal Transduction	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination Stem Cell Population Maintenance Positive Regulation Of Transcription, DNA-templated
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Prostate cancer ( 23535732) Tumor biomarkers ( 23300138)	Age at first sexual intercourse ( 34211149) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Gout (normal type) ( 32238385) Triglyceride levels ( 32203549)
Interacting Genes		14 interacting genes: AP4S1 CASP3 CCR5 CREBBP EHD4 GNB1 MED27 PHB2 PIDD1 PSMB7 PTEN SGSM2 SIRT1 XIAP	11 interacting genes: AFP ARFGAP1 ESR1 FBXO7 MED19 MED22 MED30 MED8 MED9 RBPJ SOX5
Entrez ID		174	9442
HPRD ID		00074	05438
Ensembl ID		ENSG00000081051	ENSG00000160563
Uniprot IDs		P02771	A0A024R8B7 Q6P2C8
PDB IDs		3MRK
Enriched GO Terms of Interacting Partners?
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