GUSB and GIT2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		GUSB	GIT2
Description		glucuronidase beta	GIT ArfGAP 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Membrane Azurophil Granule Lumen Lysosomal Lumen Intracellular Membrane-bounded Organelle Extracellular Exosome Ficolin-1-rich Granule Lumen	Nucleoplasm Focal Adhesion
	Molecular Function	Beta-glucuronidase Activity Signaling Receptor Binding Protein Domain Specific Binding Carbohydrate Binding	GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Carbohydrate Metabolic Process Glycosaminoglycan Catabolic Process Glucuronoside Catabolic Process	Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Catalytic Activity
Pathways		HS-GAG degradation Hyaluronan uptake and degradation MPS VII - Sly syndrome Neutrophil degranulation	CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RHOU GTPase cycle RAC3 GTPase cycle RHOV GTPase cycle
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514)	Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolic syndrome ( 20694148) Metabolite levels ( 23823483) Metabolite levels (MHPG) ( 23319000)
Interacting Genes		3 interacting genes: CES1 GIT2 PRKACA	48 interacting genes: ACTG1 ACTN1 ARHGEF6 ARHGEF7 ATF5 C4BPA CALCOCO2 CDC42 CORO1A E2F2 EDC4 GCH1 GET4 GIT1 GRK2 GUSB HGD HNRNPUL1 IKBKG KCTD5 KRT18 LAMTOR5 LMNB1 MVP NFKBIB NME2 PAK1 PAK3 PCLO POLR1B PROX1 PXN QPRT RCVRN RUFY1 RUSC2 SAFB2 SH3GLB2 SMAD3 SPOP TGFB1I1 TNFAIP3 TNIP1 TRAF1 TSN UBQLN1 USHBP1 YWHAG
Entrez ID		2990	9815
HPRD ID		02018	09779
Ensembl ID		ENSG00000169919	ENSG00000139436
Uniprot IDs		P08236	F8VXI9 F8W822 Q14161 Q68DM7 Q6FI58
PDB IDs		1BHG 3HN3
Enriched GO Terms of Interacting Partners?
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