C5AR2 and SYNGR2

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		C5AR2	SYNGR2
Description		complement C5a receptor 2	synaptogyrin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Basal Plasma Membrane Integral Component Of Membrane Apical Part Of Cell	Lipid Droplet Integral Component Of Membrane Synaptic Vesicle Membrane Neuromuscular Junction Extracellular Exosome
	Molecular Function	Complement Receptor Activity Complement Component C5a Receptor Activity G Protein-coupled Receptor Activity Protein Binding	Protein Binding
	Biological Process	Complement Receptor Mediated Signaling Pathway Chemotaxis Inflammatory Response Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Interleukin-8 Production Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Complement Component C5a Signaling Pathway Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Neutrophil Chemotaxis	Regulated Exocytosis Synaptic Vesicle Membrane Organization
Pathways		Peptide ligand-binding receptors Regulation of Complement cascade
Drugs
Diseases
GWAS			Adenocarcinoma ( 26732429) Lung cancer ( 26732429) Red blood cell count ( 32888494)
Interacting Genes		17 interacting genes: ABCA7 ACO2 C3 C4A C4orf3 C5AR1 CALM3 HAGHL HERC2 HERPUD1 PLXDC1 SCN1B SCRIB SLC25A11 SLC26A11 SYNGR2 TMEM234	9 interacting genes: BDKRB2 C5AR2 CCR4 DRD2 F2RL1 FATE1 GPR35 LTB4R2 SCARA3
Entrez ID		27202	9144
HPRD ID		17072	04891
Ensembl ID		ENSG00000134830	ENSG00000108639
Uniprot IDs		Q9P296	A0A024R8T9 O43760
PDB IDs
Enriched GO Terms of Interacting Partners?
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