C5AR2 and SLC25A11

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		C5AR2	SLC25A11
Description		complement C5a receptor 2	solute carrier family 25 member 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Basal Plasma Membrane Integral Component Of Membrane Apical Part Of Cell	Nucleus Mitochondrion Mitochondrial Inner Membrane Integral Component Of Plasma Membrane
	Molecular Function	Complement Receptor Activity Complement Component C5a Receptor Activity G Protein-coupled Receptor Activity Protein Binding	RNA Binding Protein Binding Sulfate Transmembrane Transporter Activity Thiosulfate Transmembrane Transporter Activity Oxaloacetate Transmembrane Transporter Activity Malate Transmembrane Transporter Activity Succinate Transmembrane Transporter Activity Antiporter Activity Oxoglutarate:malate Antiporter Activity
	Biological Process	Complement Receptor Mediated Signaling Pathway Chemotaxis Inflammatory Response Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Interleukin-8 Production Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Complement Component C5a Signaling Pathway Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Neutrophil Chemotaxis	Sulfate Transport Thiosulfate Transport Oxaloacetate Transport Alpha-ketoglutarate Transport Phosphate Ion Transmembrane Transport Succinate Transmembrane Transport Malate Transmembrane Transport Oxaloacetate(2-) Transmembrane Transport Sulfate Transmembrane Transport
Pathways		Peptide ligand-binding receptors Regulation of Complement cascade	Gluconeogenesis
Drugs
Diseases
GWAS			Platelet count ( 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 27863252)
Interacting Genes		17 interacting genes: ABCA7 ACO2 C3 C4A C4orf3 C5AR1 CALM3 HAGHL HERC2 HERPUD1 PLXDC1 SCN1B SCRIB SLC25A11 SLC26A11 SYNGR2 TMEM234	4 interacting genes: C5AR2 CDKN1A COPA SLC22A1
Entrez ID		27202	8402
HPRD ID		17072	05003
Ensembl ID		ENSG00000134830	ENSG00000108528
Uniprot IDs		Q9P296	Q02978 Q6IBH0
PDB IDs
Enriched GO Terms of Interacting Partners?
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