C5AR2 and PLXDC1

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		C5AR2	PLXDC1
Description		complement C5a receptor 2	plexin domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Basal Plasma Membrane Integral Component Of Membrane Apical Part Of Cell	Extracellular Region Cytoplasm Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Dendrite Neuronal Cell Body Receptor Complex
	Molecular Function	Complement Receptor Activity Complement Component C5a Receptor Activity G Protein-coupled Receptor Activity Protein Binding	Protein Binding
	Biological Process	Complement Receptor Mediated Signaling Pathway Chemotaxis Inflammatory Response Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Interleukin-8 Production Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Complement Component C5a Signaling Pathway Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Neutrophil Chemotaxis	Angiogenesis Spinal Cord Development
Pathways		Peptide ligand-binding receptors Regulation of Complement cascade
Drugs
Diseases
GWAS			Asthma ( 31619474) Tau burden ( 33426524)
Interacting Genes		17 interacting genes: ABCA7 ACO2 C3 C4A C4orf3 C5AR1 CALM3 HAGHL HERC2 HERPUD1 PLXDC1 SCN1B SCRIB SLC25A11 SLC26A11 SYNGR2 TMEM234	4 interacting genes: C5AR2 GPR35 NID1 NRF1
Entrez ID		27202	57125
HPRD ID		17072	08439
Ensembl ID		ENSG00000134830	ENSG00000161381
Uniprot IDs		Q9P296	Q8IUK5
PDB IDs
Enriched GO Terms of Interacting Partners?
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