VPS41 and AKTIP

Number of citations of the paper that reports this interaction (PubMedID 18799622)
51

Data Source:
HPRD (in vivo)

		VPS41	AKTIP
Description		VPS41 subunit of HOPS complex	AKT interacting protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Early Endosome Late Endosome Golgi Apparatus Golgi-associated Vesicle Endosome Membrane Microtubule Cytoskeleton Clathrin-coated Vesicle HOPS Complex Late Endosome Membrane Lysosomal HOPS Complex	Nucleus Cytosol Plasma Membrane FHF Complex
	Molecular Function	Protein Binding Microtubule Binding Identical Protein Binding Protein Self-association Metal Ion Binding	Protein Binding Ubiquitin-like Protein Transferase Activity Ubiquitin Conjugating Enzyme Activity
	Biological Process	Protein Targeting To Vacuole Endosome To Lysosome Transport Cellular Response To Starvation Macroautophagy Endosomal Vesicle Fusion Regulated Exocytosis Late Endosome To Lysosome Transport	Protein Polyubiquitination Positive Regulation Of Protein Phosphorylation Apoptotic Process Cellular Response To DNA Damage Stimulus Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Positive Regulation Of Protein Binding Early Endosome To Late Endosome Transport Protein Localization To Perinuclear Region Of Cytoplasm
Pathways
Drugs
Diseases
GWAS		Breast cancer and/or colorectal cancer ( 29698419) Cognitive performance ( 19734545)	Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Depressive symptoms (SSRI exposure interaction) ( 25649181) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Hip circumference adjusted for BMI ( 34021172 25673412) Serum alkaline phosphatase levels ( 33547301) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		14 interacting genes: AKTIP AP3D1 APP ARID1A ARL8B GSDME HOOK1 HOOK2 HOOK3 MON1B RAB7A RILP UBE2U ZNF512B	35 interacting genes: ACTN2 AKT1 ASS1 CEP126 CTBP2 DMXL2 DZIP3 EXOC7 FHIP1B GTF3C1 HOOK1 HOOK2 HOOK3 IMMT IPO7 LMNA MAP3K7 MARCHF5 MATR3 NEB PDE4DIP PDPK1 POLA2 RASGRF2 RPA1 TRIM23 TRIM32 TRIM41 TWNK UPF2 UTP14A VPS16 VPS18 VPS41 ZNRF2
Entrez ID		27072	64400
HPRD ID		10402	07467
Ensembl ID		ENSG00000006715	ENSG00000166971
Uniprot IDs		P49754	A0A024R6S6 A0A024R6T5 Q9H8T0
PDB IDs
Enriched GO Terms of Interacting Partners?
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