VPS41 and ARL8B

Number of citations of the paper that reports this interaction (PubMedID 25908847)
45

Data Source:
BioGRID (pull down)

		VPS41	ARL8B
Description		VPS41 subunit of HOPS complex	ADP ribosylation factor like GTPase 8B
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Early Endosome Late Endosome Golgi Apparatus Golgi-associated Vesicle Endosome Membrane Microtubule Cytoskeleton Clathrin-coated Vesicle HOPS Complex Late Endosome Membrane Lysosomal HOPS Complex	Cytoplasm Lysosome Lysosomal Membrane Vacuolar Membrane Cytosol Membrane Midbody Late Endosome Membrane Synapse Spindle Midzone Extracellular Exosome Cytolytic Granule Membrane Axon Cytoplasm
	Molecular Function	Protein Binding Microtubule Binding Identical Protein Binding Protein Self-association Metal Ion Binding	GTPase Activity G Protein Activity Protein Binding GTP Binding GDP Binding Alpha-tubulin Binding Beta-tubulin Binding
	Biological Process	Protein Targeting To Vacuole Endosome To Lysosome Transport Cellular Response To Starvation Macroautophagy Endosomal Vesicle Fusion Regulated Exocytosis Late Endosome To Lysosome Transport	Plasma Membrane Repair Antigen Processing And Presentation Of Polysaccharide Antigen Via MHC Class II Antigen Processing And Presentation Following Phagocytosis Cell Cycle Chromosome Segregation Anterograde Axonal Transport Protein Transport Endosomal Transport Lysosome Localization Natural Killer Cell Mediated Cytotoxicity Viral Exocytosis Cell Division Autophagosome-lysosome Fusion Endosome To Lysosome Transport Of Low-density Lipoprotein Particle Phagosome-lysosome Fusion Late Endosome To Lysosome Transport Calcium Ion Regulated Lysosome Exocytosis
Pathways
Drugs
Diseases
GWAS		Breast cancer and/or colorectal cancer ( 29698419) Cognitive performance ( 19734545)	Disc degeneration (lumbar) ( 22993228) Fulminant type 1 diabetes ( 30552108) Metabolite levels ( 23823483) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		14 interacting genes: AKTIP AP3D1 APP ARID1A ARL8B GSDME HOOK1 HOOK2 HOOK3 MON1B RAB7A RILP UBE2U ZNF512B	11 interacting genes: AMH APP ATP5MF BTN3A3 CIDEB DLEU1 SLC30A8 TGFBR1 TMEM14B TUBB VPS41
Entrez ID		27072	55207
HPRD ID		10402	12483
Ensembl ID		ENSG00000006715	ENSG00000134108
Uniprot IDs		P49754	Q9NVJ2
PDB IDs			2AL7
Enriched GO Terms of Interacting Partners?
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