AKTIP and ZNRF2

Number of citations of the paper that reports this interaction (PubMedID 32265276)
1

Data Source:
BioGRID (two hybrid)

		AKTIP	ZNRF2
Description		AKT interacting protein	zinc and ring finger 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane FHF Complex	Fibrillar Center Nucleoplasm Cytoplasm Lysosomal Membrane Cytosol Plasma Membrane Endosome Membrane Cytoplasmic Vesicle Membrane Protein-containing Complex Presynaptic Membrane Cell Projection Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Ubiquitin-like Protein Transferase Activity Ubiquitin Conjugating Enzyme Activity	Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Positive Regulation Of Protein Phosphorylation Apoptotic Process Cellular Response To DNA Damage Stimulus Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Positive Regulation Of Protein Binding Early Endosome To Late Endosome Transport Protein Localization To Perinuclear Region Of Cytoplasm	Protein Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Depressive symptoms (SSRI exposure interaction) ( 25649181) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Hip circumference adjusted for BMI ( 34021172 25673412) Serum alkaline phosphatase levels ( 33547301) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Cadmium levels ( 26025379)
Interacting Genes		35 interacting genes: ACTN2 AKT1 ASS1 CEP126 CTBP2 DMXL2 DZIP3 EXOC7 FHIP1B GTF3C1 HOOK1 HOOK2 HOOK3 IMMT IPO7 LMNA MAP3K7 MARCHF5 MATR3 NEB PDE4DIP PDPK1 POLA2 RASGRF2 RPA1 TRIM23 TRIM32 TRIM41 TWNK UPF2 UTP14A VPS16 VPS18 VPS41 ZNRF2	16 interacting genes: AKTIP ATP1A1 MTOR PPP6C UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2T UBE2V1 UBE2W
Entrez ID		64400	223082
HPRD ID		07467	15894
Ensembl ID		ENSG00000166971	ENSG00000180233
Uniprot IDs		A0A024R6S6 A0A024R6T5 Q9H8T0	A0A090N8Y8 Q8NHG8
PDB IDs
Enriched GO Terms of Interacting Partners?
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