POLDIP2 and CPE

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		POLDIP2	CPE
Description		DNA polymerase delta interacting protein 2	carboxypeptidase E
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Plasma Membrane Cell-cell Junction Midbody Mitochondrial Nucleoid Mitotic Spindle	Extracellular Space Golgi Apparatus Plasma Membrane Transport Vesicle Membrane Extracellular Exosome
	Molecular Function	DNA Binding Protein Binding	Carboxypeptidase Activity Metallocarboxypeptidase Activity Protein Binding Zinc Ion Binding Neurexin Family Protein Binding Cell Adhesion Molecule Binding
	Biological Process	Negative Regulation Of Macroautophagy Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Focal Adhesion Assembly Mitochondrion Morphogenesis Error-free Translesion Synthesis Mitotic Spindle Assembly Positive Regulation Of Mitotic Cytokinesis Positive Regulation Of Actin Filament Binding Vascular Associated Smooth Muscle Cell Proliferation Positive Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity	Cardiac Left Ventricle Morphogenesis Cellular Protein Modification Process Peptide Metabolic Process Neuropeptide Signaling Pathway Wnt Signaling Pathway Protein Processing Protein Localization To Membrane
Pathways			Insulin processing
Drugs			Insulin human Insulin pork
Diseases
GWAS		Blood protein levels ( 29875488) Osteoprotegerin levels ( 25080503)	Pelvic organ prolapse (moderate/severe) ( 26545240) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		20 interacting genes: AGTRAP ALAS1 APP ASCC2 CHCHD2 CPE DNAAF6 FBXO7 HDAC6 MAD2L2 MTUS2 PCNA PDPK1 POLD2 POLN PTEN REV1 SELENBP1 TAB1 TMEM97	18 interacting genes: BDNF CCK CHD3 CNTNAP2 GAST GCG GTF3C1 INS LRIF1 MED31 NTS PMCH POLA2 POLDIP2 ROBO2 RPA1 TRH UTP14A
Entrez ID		26073	1363
HPRD ID		17874	00272
Ensembl ID		ENSG00000004142	ENSG00000109472
Uniprot IDs		B4DEM9 Q9Y2S7	A0A384N679 P16870
PDB IDs		6Z9C
Enriched GO Terms of Interacting Partners?
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