CPE and POLDIP2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CPE	POLDIP2
Description		carboxypeptidase E	DNA polymerase delta interacting protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Golgi Apparatus Plasma Membrane Transport Vesicle Membrane Extracellular Exosome	Nucleus Mitochondrion Mitochondrial Matrix Plasma Membrane Cell-cell Junction Midbody Mitochondrial Nucleoid Mitotic Spindle
	Molecular Function	Carboxypeptidase Activity Metallocarboxypeptidase Activity Protein Binding Zinc Ion Binding Neurexin Family Protein Binding Cell Adhesion Molecule Binding	DNA Binding Protein Binding
	Biological Process	Cardiac Left Ventricle Morphogenesis Cellular Protein Modification Process Peptide Metabolic Process Neuropeptide Signaling Pathway Wnt Signaling Pathway Protein Processing Protein Localization To Membrane	Negative Regulation Of Macroautophagy Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Focal Adhesion Assembly Mitochondrion Morphogenesis Error-free Translesion Synthesis Mitotic Spindle Assembly Positive Regulation Of Mitotic Cytokinesis Positive Regulation Of Actin Filament Binding Vascular Associated Smooth Muscle Cell Proliferation Positive Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity
Pathways		Insulin processing
Drugs		Insulin human Insulin pork
Diseases
GWAS		Pelvic organ prolapse (moderate/severe) ( 26545240) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Blood protein levels ( 29875488) Osteoprotegerin levels ( 25080503)
Interacting Genes		18 interacting genes: BDNF CCK CHD3 CNTNAP2 GAST GCG GTF3C1 INS LRIF1 MED31 NTS PMCH POLA2 POLDIP2 ROBO2 RPA1 TRH UTP14A	20 interacting genes: AGTRAP ALAS1 APP ASCC2 CHCHD2 CPE DNAAF6 FBXO7 HDAC6 MAD2L2 MTUS2 PCNA PDPK1 POLD2 POLN PTEN REV1 SELENBP1 TAB1 TMEM97
Entrez ID		1363	26073
HPRD ID		00272	17874
Ensembl ID		ENSG00000109472	ENSG00000004142
Uniprot IDs		A0A384N679 P16870	B4DEM9 Q9Y2S7
PDB IDs			6Z9C
Enriched GO Terms of Interacting Partners?
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