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POLDIP2 and POLD2
Number of citations of the paper that reports this interaction (PubMedID
12522211
)
41
Data Source:
HPRD
(two hybrid, in vivo, in vitro)
POLDIP2
POLD2
Description
DNA polymerase delta interacting protein 2
DNA polymerase delta 2, accessory subunit
Image
GO Annotations
Cellular Component
Nucleus
Mitochondrion
Mitochondrial Matrix
Plasma Membrane
Cell-cell Junction
Midbody
Mitochondrial Nucleoid
Mitotic Spindle
Nucleus
Nucleoplasm
Zeta DNA Polymerase Complex
DNA Polymerase Complex
Delta DNA Polymerase Complex
Molecular Function
DNA Binding
Protein Binding
DNA Binding
Protein Binding
Biological Process
Negative Regulation Of Macroautophagy
Positive Regulation Of Mitotic Cell Cycle
Positive Regulation Of Focal Adhesion Assembly
Mitochondrion Morphogenesis
Error-free Translesion Synthesis
Mitotic Spindle Assembly
Positive Regulation Of Mitotic Cytokinesis
Positive Regulation Of Actin Filament Binding
Vascular Associated Smooth Muscle Cell Proliferation
Positive Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity
DNA Replication
DNA Strand Elongation Involved In DNA Replication
DNA Repair
DNA Biosynthetic Process
Pathways
Recognition of DNA damage by PCNA-containing replication complex
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Removal of the Flap Intermediate from the C-strand
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
PCNA-Dependent Long Patch Base Excision Repair
Termination of translesion DNA synthesis
HDR through Homologous Recombination (HRR)
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Polymerase switching
Removal of the Flap Intermediate
Processive synthesis on the lagging strand
Drugs
Diseases
GWAS
Blood protein levels (
29875488
)
Osteoprotegerin levels (
25080503
)
Interacting Genes
20 interacting genes:
AGTRAP
ALAS1
APP
ASCC2
CHCHD2
CPE
DNAAF6
FBXO7
HDAC6
MAD2L2
MTUS2
PCNA
PDPK1
POLD2
POLN
PTEN
REV1
SELENBP1
TAB1
TMEM97
19 interacting genes:
CCHCR1
CDK2
CDKN1A
EP300
ERBB2
KCTD13
LSM6
OGT
PCNA
POLD1
POLD3
POLD4
POLDIP2
POLDIP3
POLH
SOX12
WRN
WRNIP1
XRN1
Entrez ID
26073
5425
HPRD ID
17874
15982
Ensembl ID
ENSG00000004142
ENSG00000106628
Uniprot IDs
B4DEM9
Q9Y2S7
A0A087WWF6
P49005
PDB IDs
6Z9C
3E0J
6S1M
6S1N
6S1O
6TNY
6TNZ
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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