CPE and GTF3C1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CPE	GTF3C1
Description		carboxypeptidase E	general transcription factor IIIC subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Golgi Apparatus Plasma Membrane Transport Vesicle Membrane Extracellular Exosome	Transcription Factor TFIIIC Complex Nucleoplasm Nucleolus Membrane Ribonucleoprotein Complex
	Molecular Function	Carboxypeptidase Activity Metallocarboxypeptidase Activity Protein Binding Zinc Ion Binding Neurexin Family Protein Binding Cell Adhesion Molecule Binding	DNA Binding Protein Binding
	Biological Process	Cardiac Left Ventricle Morphogenesis Cellular Protein Modification Process Peptide Metabolic Process Neuropeptide Signaling Pathway Wnt Signaling Pathway Protein Processing Protein Localization To Membrane	Transcription By RNA Polymerase III Transcription Initiation From RNA Polymerase III Promoter RRNA Transcription TRNA Transcription 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III
Pathways		Insulin processing	RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs		Insulin human Insulin pork
Diseases
GWAS		Pelvic organ prolapse (moderate/severe) ( 26545240) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Asthma ( 31959851) Lymphocyte percentage of white cells ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Red blood cell count ( 32888494)
Interacting Genes		18 interacting genes: BDNF CCK CHD3 CNTNAP2 GAST GCG GTF3C1 INS LRIF1 MED31 NTS PMCH POLA2 POLDIP2 ROBO2 RPA1 TRH UTP14A	23 interacting genes: AGTRAP AKTIP ASCC2 CHN1 CMTM5 CPE CSNK1E DEDD EZH2 FGFR3 GTF3C4 HGH1 IGFBP3 KLF6 MAGEA4 MAPK10 PRPF38A RBM23 SNU13 SUMO2 SUPT5H TBC1D17 UBE3A
Entrez ID		1363	2975
HPRD ID		00272	07540
Ensembl ID		ENSG00000109472	ENSG00000077235
Uniprot IDs		A0A384N679 P16870	Q12789
PDB IDs
Enriched GO Terms of Interacting Partners?
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