SMUG1 and KRTAP8-1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SMUG1	KRTAP8-1
Description		single-strand-selective monofunctional uracil-DNA glycosylase 1	keratin associated protein 8-1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Nucleolus Cytosol	Cytosol Intermediate Filament
	Molecular Function	Oxidized Pyrimidine Nucleobase Lesion DNA N-glycosylase Activity DNA Binding Uracil DNA N-glycosylase Activity Protein Binding Single-strand Selective Uracil DNA N-glycosylase Activity DNA N-glycosylase Activity	Protein Binding
	Biological Process	Base-excision Repair Depyrimidination
Pathways		Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Displacement of DNA glycosylase by APEX1	Keratinization
Drugs
Diseases
GWAS		Coronary artery disease ( 32469254) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Gut microbiota (bacterial taxa) ( 27723756) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		37 interacting genes: C10orf55 CDC23 CRX CYSRT1 GLYCTK GPS2 HNRNPF INCA1 KCTD9 KLHDC7B KRTAP13-2 KRTAP15-1 KRTAP26-1 KRTAP6-2 KRTAP8-1 LMO2 MGAT5B NEK6 NOXA1 PEF1 PRKAB2 PROP1 PRR13 PRR35 RBPMS SKIL SMARCD1 SPAG8 TCF7L2 TEKT5 TFG TRAPPC6A TRIP13 VAC14 VENTX YPEL3 ZIC1	78 interacting genes: AANAT AGXT AOC1 ARID5A ATG9A ATXN1L BANP BCAS2 BHLHE40 C11orf16 C1orf94 C20orf85 CAMK2A CCDC17 CCNK CDA CERCAM CREB5 CRYAB CYSRT1 DAB1 DAZAP2 DMRTB1 DTX2 FAAP20 FAM168A FAM83A FOXD2 FOXP3 GATA2 GCM2 GLIS2 HEY2 HOXC8 HYPK KRTAP12-4 KRTAP19-5 KRTAP26-1 MFSD13A MKRN3 MYOZ3 NKX2-5 NOXA1 P4HA3 PAX3 PITX1 PLSCR4 POGZ POU6F2 PPP1R32 PROP1 PRR13 PRR35 PSMA3 RAMAC RBPMS RBPMS2 RNF38 RUSC1 SMR3A SMUG1 SNRPC TBX18 TEKT3 TIAL1 TLE5 TLX3 TMSB4X TNIP1 TNPO2 TSPYL6 VENTX VEZF1 YTHDF1 ZBTB32 ZC3H10 ZIC1 ZNF34
Entrez ID		23583	337879
HPRD ID		06376	11221
Ensembl ID		ENSG00000123415	ENSG00000183640
Uniprot IDs		A0A024RAZ8 A0A0S2Z526 Q53HV7	Q8IUC2
PDB IDs
Enriched GO Terms of Interacting Partners?
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