KRTAP8-1 and AOC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KRTAP8-1	AOC1
Description		keratin associated protein 8-1	amine oxidase copper containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Extracellular Region Extracellular Space Peroxisome Plasma Membrane Bicellular Tight Junction Specific Granule Lumen Extracellular Exosome
	Molecular Function	Protein Binding	Copper Ion Binding Calcium Ion Binding Protein Binding Primary Amine Oxidase Activity Heparin Binding Zinc Ion Binding Protein Homodimerization Activity Protein-containing Complex Binding Quinone Binding Diamine Oxidase Activity Histamine Oxidase Activity Methylputrescine Oxidase Activity Propane-1,3-diamine Oxidase Activity
	Biological Process		Amine Metabolic Process Putrescine Metabolic Process Cellular Response To Copper Ion Starvation Response To Antibiotic Cellular Response To Copper Ion Cellular Response To Histamine Cellular Response To Heparin Cellular Response To Azide
Pathways		Keratinization	Phase I - Functionalization of compounds Neutrophil degranulation
Drugs			Amiloride Calcium Diminazene
Diseases
GWAS		Gut microbiota (bacterial taxa) ( 27723756) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)	Anthropometric traits (multi-trait analysis) ( 30166351) Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 30072576) Carpal tunnel syndrome ( 30833571) Eyebrow thickness ( 26926045) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Low hand grip strength (60 years and older) (EWGSOP) ( 33510174) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Multisite chronic pain ( 33830993) Serum alkaline phosphatase levels ( 33547301) Serum metabolite concentrations in chronic kidney disease ( 29545352) Triglyceride levels ( 32203549) Triglycerides ( 30275531) Type 2 diabetes ( 30297969) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		78 interacting genes: AANAT AGXT AOC1 ARID5A ATG9A ATXN1L BANP BCAS2 BHLHE40 C11orf16 C1orf94 C20orf85 CAMK2A CCDC17 CCNK CDA CERCAM CREB5 CRYAB CYSRT1 DAB1 DAZAP2 DMRTB1 DTX2 FAAP20 FAM168A FAM83A FOXD2 FOXP3 GATA2 GCM2 GLIS2 HEY2 HOXC8 HYPK KRTAP12-4 KRTAP19-5 KRTAP26-1 MFSD13A MKRN3 MYOZ3 NKX2-5 NOXA1 P4HA3 PAX3 PITX1 PLSCR4 POGZ POU6F2 PPP1R32 PROP1 PRR13 PRR35 PSMA3 RAMAC RBPMS RBPMS2 RNF38 RUSC1 SMR3A SMUG1 SNRPC TBX18 TEKT3 TIAL1 TLE5 TLX3 TMSB4X TNIP1 TNPO2 TSPYL6 VENTX VEZF1 YTHDF1 ZBTB32 ZC3H10 ZIC1 ZNF34	13 interacting genes: CYB561A3 DAO DAZAP2 DNM2 FGD1 FOXH1 KRTAP8-1 NTAQ1 POGZ RBPMS2 TIAL1 TLX3 ZC3H10
Entrez ID		337879	26
HPRD ID		11221	00088
Ensembl ID		ENSG00000183640	ENSG00000002726
Uniprot IDs		Q8IUC2	P19801
PDB IDs			3HI7 3HIG 3HII 3K5T 3MPH
Enriched GO Terms of Interacting Partners?
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