SMUG1 and KRTAP26-1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SMUG1	KRTAP26-1
Description		single-strand-selective monofunctional uracil-DNA glycosylase 1	keratin associated protein 26-1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Nucleolus Cytosol	Cytosol Intermediate Filament
	Molecular Function	Oxidized Pyrimidine Nucleobase Lesion DNA N-glycosylase Activity DNA Binding Uracil DNA N-glycosylase Activity Protein Binding Single-strand Selective Uracil DNA N-glycosylase Activity DNA N-glycosylase Activity	Protein Binding
	Biological Process	Base-excision Repair Depyrimidination
Pathways		Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Displacement of DNA glycosylase by APEX1	Keratinization
Drugs
Diseases
GWAS		Coronary artery disease ( 32469254) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		37 interacting genes: C10orf55 CDC23 CRX CYSRT1 GLYCTK GPS2 HNRNPF INCA1 KCTD9 KLHDC7B KRTAP13-2 KRTAP15-1 KRTAP26-1 KRTAP6-2 KRTAP8-1 LMO2 MGAT5B NEK6 NOXA1 PEF1 PRKAB2 PROP1 PRR13 PRR35 RBPMS SKIL SMARCD1 SPAG8 TCF7L2 TEKT5 TFG TRAPPC6A TRIP13 VAC14 VENTX YPEL3 ZIC1	91 interacting genes: ACY3 ARID5A C19orf54 CARD10 CCNJL CELF5 CERCAM CFAP206 COL8A1 CYSRT1 DAZAP2 DTX2 EFEMP2 FAM168B FAM222B GDPD5 GRN HGS HNF1B HOXA1 ID3 INTS11 KRT34 KRTAP1-1 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP13-2 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP3-1 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-7 KRTAP5-6 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 KRTAP9-2 KRTAP9-8 LASP1 LCE2B MAPKBP1 MGAT5B NBPF19 NHLRC4 NOTCH2NLA OTX1 PITX1 PLA2G10 PM20D2 PRR22 PRR35 PSMA3 RASD1 RBPMS RECK RHOXF2 RNF208 SF1 SIVA1 SLC15A2 SMARCC1 SMUG1 SPAG8 SPATA12 SSC4D STK16 TEKT3 TEKT4 TENT5A TEX37 TFAP2D TFG TOX TRIM42 TRIP13 TRIP6 VASN VENTX YTHDF1 ZNF34
Entrez ID		23583	388818
HPRD ID		06376	14206
Ensembl ID		ENSG00000123415	ENSG00000197683
Uniprot IDs		A0A024RAZ8 A0A0S2Z526 Q53HV7	Q6PEX3
PDB IDs
Enriched GO Terms of Interacting Partners?
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