SMUG1

Description		single-strand-selective monofunctional uracil-DNA glycosylase 1
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Nucleolus Cytosol
	Molecular Function	Oxidized Pyrimidine Nucleobase Lesion DNA N-glycosylase Activity DNA Binding Uracil DNA N-glycosylase Activity Protein Binding Single-strand Selective Uracil DNA N-glycosylase Activity DNA N-glycosylase Activity
	Biological Process	Base-excision Repair Depyrimidination
Pathways		Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Displacement of DNA glycosylase by APEX1
Drugs
Diseases
GWAS		Coronary artery disease ( 32469254) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		37 interacting genes: C10orf55 CDC23 CRX CYSRT1 GLYCTK GPS2 HNRNPF INCA1 KCTD9 KLHDC7B KRTAP13-2 KRTAP15-1 KRTAP26-1 KRTAP6-2 KRTAP8-1 LMO2 MGAT5B NEK6 NOXA1 PEF1 PRKAB2 PROP1 PRR13 PRR35 RBPMS SKIL SMARCD1 SPAG8 TCF7L2 TEKT5 TFG TRAPPC6A TRIP13 VAC14 VENTX YPEL3 ZIC1
Entrez ID		23583
HPRD ID		06376
Ensembl ID		ENSG00000123415
Uniprot IDs		A0A024RAZ8 A0A0S2Z526 Q53HV7
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?