SMUG1 and GLYCTK

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SMUG1	GLYCTK
Description		single-strand-selective monofunctional uracil-DNA glycosylase 1	glycerate kinase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Nucleolus Cytosol	Cytoplasm Mitochondrion Golgi Apparatus Cytosol
	Molecular Function	Oxidized Pyrimidine Nucleobase Lesion DNA N-glycosylase Activity DNA Binding Uracil DNA N-glycosylase Activity Protein Binding Single-strand Selective Uracil DNA N-glycosylase Activity DNA N-glycosylase Activity	Protein Binding ATP Binding Glycerate Kinase Activity
	Biological Process	Base-excision Repair Depyrimidination	Protein Phosphorylation Fructose Catabolic Process To Hydroxyacetone Phosphate And Glyceraldehyde-3-phosphate
Pathways		Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Displacement of DNA glycosylase by APEX1	Fructose catabolism
Drugs
Diseases
GWAS		Coronary artery disease ( 32469254) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Hemoglobin levels ( 32327693) Schizophrenia ( 28991256 23974872)
Interacting Genes		37 interacting genes: C10orf55 CDC23 CRX CYSRT1 GLYCTK GPS2 HNRNPF INCA1 KCTD9 KLHDC7B KRTAP13-2 KRTAP15-1 KRTAP26-1 KRTAP6-2 KRTAP8-1 LMO2 MGAT5B NEK6 NOXA1 PEF1 PRKAB2 PROP1 PRR13 PRR35 RBPMS SKIL SMARCD1 SPAG8 TCF7L2 TEKT5 TFG TRAPPC6A TRIP13 VAC14 VENTX YPEL3 ZIC1	59 interacting genes: ADAMTSL4 ANKRD53 ARMC5 ATP23 BAIAP2L2 C19orf54 CALCOCO2 CEP70 DTX2 EFHC2 GMPPB GOLGA2 IHO1 KLHL12 KRT13 KRT15 KRT19 KRT34 KRT75 KRTAP19-5 KRTAP6-2 KRTAP6-3 LZTS2 MAGED1 METTL15 METTL27 MGAT5B MIS18A MORN3 NFKBID NOTO NT5C2 PFDN5 PICK1 PLAGL2 POMC PRDM14 PUDP RBCK1 RBPMS REL SAXO1 SERTAD1 SMUG1 SNF8 SPAG8 SPRED1 STK33 TRIM27 TRIM42 TRIP13 TUBGCP4 UBP1 UFSP1 ZFP90 ZG16 ZIM2 ZNF620 ZNF688
Entrez ID		23583	132158
HPRD ID		06376	13586
Ensembl ID		ENSG00000123415	ENSG00000168237
Uniprot IDs		A0A024RAZ8 A0A0S2Z526 Q53HV7	A1LQE8 Q8IVS8
PDB IDs
Enriched GO Terms of Interacting Partners?
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