SMC5 and SLF2

Number of citations of the paper that reports this interaction (PubMedID 32389690)
5

Data Source:
BioGRID (two hybrid, pull down)

		SMC5	SLF2
Description		structural maintenance of chromosomes 5	SMC5-SMC6 complex localization factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromosome, Telomeric Region Sex Chromosome Nucleus Nucleoplasm Cytoplasm PML Body Nuclear Speck Cell Junction Smc5-Smc6 Complex Interchromatin Granule Site Of Double-strand Break	Chromatin Nucleus Nucleoplasm Site Of Double-strand Break Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding ATP Binding	Protein Binding Ubiquitin Protein Ligase Binding Protein-containing Complex Binding
	Biological Process	Telomere Maintenance Via Recombination Double-strand Break Repair Via Homologous Recombination Double-strand Break Repair Via Nonhomologous End Joining Cellular Response To DNA Damage Stimulus Sister Chromatid Cohesion Internal Peptidyl-lysine Acetylation Stem Cell Population Maintenance Chromosome Condensation Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion Mitotic Cell Cycle Phase Transition Cell Division Positive Regulation Of Chromosome Segregation Protein Localization To Chromosome, Centromeric Region Cellular Senescence	DNA Repair Cellular Response To DNA Damage Stimulus Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion Protein Localization To Site Of Double-strand Break Positive Regulation Of Double-strand Break Repair
Pathways		SUMOylation of DNA damage response and repair proteins
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 27089180)	Age at first birth ( 34211149) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lung cancer ( 28604730)
Interacting Genes		6 interacting genes: DISC1 EID3 NSMCE2 SLF2 SMN1 TK1	8 interacting genes: CALM1 OPTN PSMA1 SFMBT2 SLF1 SMC5 SMC6 TRIM14
Entrez ID		23137	55719
HPRD ID		10241	12581
Ensembl ID		ENSG00000198887	ENSG00000119906
Uniprot IDs		Q8IY18	Q8IX21
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?