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SMC5

Description structural maintenance of chromosomes 5
Image No pdb structure
GO Annotations Cellular Component
  • Chromosome, Centromeric Region
  • Chromosome, Telomeric Region
  • Sex Chromosome
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • PML Body
  • Nuclear Speck
  • Cell Junction
  • Smc5-Smc6 Complex
  • Interchromatin Granule
  • Site Of Double-strand Break
Molecular Function
  • Protein Binding
  • ATP Binding
Biological Process
  • Telomere Maintenance Via Recombination
  • Double-strand Break Repair Via Homologous Recombination
  • Double-strand Break Repair Via Nonhomologous End Joining
  • Cellular Response To DNA Damage Stimulus
  • Sister Chromatid Cohesion
  • Internal Peptidyl-lysine Acetylation
  • Stem Cell Population Maintenance
  • Chromosome Condensation
  • Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion
  • Mitotic Cell Cycle Phase Transition
  • Cell Division
  • Positive Regulation Of Chromosome Segregation
  • Protein Localization To Chromosome, Centromeric Region
  • Cellular Senescence
Pathways
  • SUMOylation of DNA damage response and repair proteins
Drugs
Diseases
GWAS
  • Age at first sexual intercourse ( 27089180)
Interacting Genes 6 interacting genes: DISC1 EID3 NSMCE2 SLF2 SMN1 TK1
Entrez ID 23137
HPRD ID 10241
Ensembl ID ENSG00000198887
Uniprot IDs Q8IY18
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025