SLF2 and SLF1

Number of citations of the paper that reports this interaction (PubMedID 26496610)
430

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		SLF2	SLF1
Description		SMC5-SMC6 complex localization factor 2	SMC5-SMC6 complex localization factor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Site Of Double-strand Break Intracellular Membrane-bounded Organelle	Nucleosome Nucleus Nucleoplasm Cytoplasm Centrosome Site Of Double-strand Break Nuclear Inclusion Body
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Protein-containing Complex Binding	Protein Binding Ubiquitin Protein Ligase Binding Protein-containing Complex Binding
	Biological Process	DNA Repair Cellular Response To DNA Damage Stimulus Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion Protein Localization To Site Of Double-strand Break Positive Regulation Of Double-strand Break Repair	DNA Repair Cellular Response To DNA Damage Stimulus Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion Protein Localization To Site Of Double-strand Break Positive Regulation Of Double-strand Break Repair
Pathways
Drugs
Diseases
GWAS		Age at first birth ( 34211149) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lung cancer ( 28604730)
Interacting Genes		8 interacting genes: CALM1 OPTN PSMA1 SFMBT2 SLF1 SMC5 SMC6 TRIM14	2 interacting genes: SLF2 USP21
Entrez ID		55719	84250
HPRD ID		12581	08538
Ensembl ID		ENSG00000119906	ENSG00000133302
Uniprot IDs		Q8IX21	I6L9F1 Q9BQI6
PDB IDs
Enriched GO Terms of Interacting Partners?
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