ARHGAP26 and CDC42EP2

Number of citations of the paper that reports this interaction (PubMedID 26871637)
172

Data Source:
BioGRID (two hybrid)

		ARHGAP26	CDC42EP2
Description		Rho GTPase activating protein 26	CDC42 effector protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytosol Cytoskeleton Focal Adhesion	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Endomembrane System Microtubule Cytoskeleton Membrane Phagocytic Vesicle
	Molecular Function	GTPase Activator Activity Protein Binding Phospholipid Binding	Opioid Peptide Activity GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Signal Transduction Nervous System Development Actin Cytoskeleton Organization Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction	Actin Filament Organization Rho Protein Signal Transduction Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Protein-containing Complex Assembly Regulation Of Catalytic Activity Cellular Response To Interferon-gamma
Pathways		RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle	MAPK6/MAPK4 signaling CDC42 GTPase cycle RHOQ GTPase cycle
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Coronary artery disease ( 29212778) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Heel bone mineral density ( 30598549 28869591) Height ( 31562340) LDL cholesterol levels in HIV infection ( 33109212) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Myocardial infarction ( 33532862) Night sleep phenotypes ( 27126917) PR interval ( 32439900) Pulse pressure ( 27841878) Septic shock resolution ( 32755526) Suicide attempt severity in mood disorders ( 33783297) Waist circumference ( 28552196)	Acne (severe) ( 24927181) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252)
Interacting Genes		9 interacting genes: ACSL6 CDC42 CDC42EP2 INSR PKN1 PKN3 PTK2 RHOA SRPK1	11 interacting genes: ARHGAP26 CASS4 CDC42 COX5B NEDD9 NME7 PICK1 RHOQ SEPTIN6 SEPTIN7 SNCA
Entrez ID		23092	10435
HPRD ID		05643	09363
Ensembl ID		ENSG00000145819	ENSG00000149798
Uniprot IDs		A0A0S2Z536 Q9UNA1	O14613
PDB IDs		1UGV
Enriched GO Terms of Interacting Partners?
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